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Original article
Submitted: 2021-10-12
Accepted: 2021-11-05
Published online: 2021-11-09
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Performance of rupture-related morphological parameters in posterior communicating artery aneurysms with fetal-type variant

S. Chen1, C. Li2, C. Karmonik3, Y. Cheng1, N. Lv4
DOI: 10.5603/FM.a2021.0123
·
Pubmed: 34783002
Affiliations
  1. Shanghai Interventional Medical Device Engineering Technology Research Center, University of Shanghai for Science and Technology, Shanghai, China
  2. Department of Geriatrics, Dongying New District Hospital, Dongying, China
  3. MRI Core, Houston Methodist Research Institute, Houston, Texas, United States
  4. Department of Neurosurgery, Changhai Hospital, Second Military Medical University, Shanghai, China

open access

Ahead of Print
ORIGINAL ARTICLES
Submitted: 2021-10-12
Accepted: 2021-11-05
Published online: 2021-11-09

Abstract

Background: To investigate the impact of fetal-type posterior cerebral artery (fPCA) variant on morphological parameters of posterior communicating artery (PComA) aneurysms for rupture risk assessment.

Materials and methods: A total of 98 PComA aneurysms (62 ruptured and 36 unruptured) in 98 consecutive patients were reviewed. Morphological parameters were calculated including aneurysm size, aspect ratio (AR), size ratio (SR), dome-to-neck ratio (DN), bottleneck factor (BNF) and inflow angle. Performance of morphological parameters to discriminate rupture status were compared between aneurysms with or without fPCA.

Results: fPCA variant was determined in 39 (39.8%, 25 ruptured and 14 unruptured) lesions. The ruptured group revealed a significantly larger size (P=0.004), AR (P=0.003), SR (P=0.001), and inflow angle (P<0.001). For the aneurysms without fPCA, all morphological parameters were significantly different between ruptured and unruptured aneurysms (P<0.05); for the aneurysms with fPCA, only inflow angle (P=0.001) was significantly related with the rupture status. Multivariate analysis showed that SR (P=0.035 and P=0.011) and inflow angle (P=0.001 and P=0.028) were independent rupture risk factors for the total cohort and the aneurysms without fPCA; while only inflow angle (P=0.004) revealed to be independently related with rupture status of aneurysms without fPCA.

Conclusions: The performance of morphological parameters to discriminate rupture status were different between PComA Aneurysms with and without fPCA variants. Inflow angle might be a reliable predictor for rupture risk of PComA aneurysms.

Abstract

Background: To investigate the impact of fetal-type posterior cerebral artery (fPCA) variant on morphological parameters of posterior communicating artery (PComA) aneurysms for rupture risk assessment.

Materials and methods: A total of 98 PComA aneurysms (62 ruptured and 36 unruptured) in 98 consecutive patients were reviewed. Morphological parameters were calculated including aneurysm size, aspect ratio (AR), size ratio (SR), dome-to-neck ratio (DN), bottleneck factor (BNF) and inflow angle. Performance of morphological parameters to discriminate rupture status were compared between aneurysms with or without fPCA.

Results: fPCA variant was determined in 39 (39.8%, 25 ruptured and 14 unruptured) lesions. The ruptured group revealed a significantly larger size (P=0.004), AR (P=0.003), SR (P=0.001), and inflow angle (P<0.001). For the aneurysms without fPCA, all morphological parameters were significantly different between ruptured and unruptured aneurysms (P<0.05); for the aneurysms with fPCA, only inflow angle (P=0.001) was significantly related with the rupture status. Multivariate analysis showed that SR (P=0.035 and P=0.011) and inflow angle (P=0.001 and P=0.028) were independent rupture risk factors for the total cohort and the aneurysms without fPCA; while only inflow angle (P=0.004) revealed to be independently related with rupture status of aneurysms without fPCA.

Conclusions: The performance of morphological parameters to discriminate rupture status were different between PComA Aneurysms with and without fPCA variants. Inflow angle might be a reliable predictor for rupture risk of PComA aneurysms.

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Keywords

intracranial aneurysm, rupture, morphology

About this article
Title

Performance of rupture-related morphological parameters in posterior communicating artery aneurysms with fetal-type variant

Journal

Folia Morphologica

Issue

Ahead of Print

Article type

Original article

Published online

2021-11-09

Page views

336

Article views/downloads

188

DOI

10.5603/FM.a2021.0123

Pubmed

34783002

Keywords

intracranial aneurysm
rupture
morphology

Authors

S. Chen
C. Li
C. Karmonik
Y. Cheng
N. Lv

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