open access

Vol 79, No 4 (2020)
Original article
Published online: 2019-12-20
Submitted: 2019-10-24
Accepted: 2019-11-28
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Evaluation of the frequency of left renal vein variations in computed tomography and its relationship with cancer development

T. Y. Kuzan, B. N. Kuzan, T. A. Telli, D. Tüney
DOI: 10.5603/FM.a2019.0137
·
Pubmed: 31886880
·
Folia Morphol 2020;79(4):793-798.

open access

Vol 79, No 4 (2020)
ORIGINAL ARTICLES
Published online: 2019-12-20
Submitted: 2019-10-24
Accepted: 2019-11-28

Abstract

Background: Left renal vein (LRV) variations occur in 0.8–10.2% of the population. The most common LRV variations are retroaortic left renal vein (RLRV) and circumaortic left renal vein (CLRV). The purpose of this study is to determine the frequency of LRV variations in a large series on computed tomography (CT) and to investigate the association between LRV and malignancy development.

Materials and methods: Between January 2015 and January 2017, an abdominal CT examination of 12,341 (5505 female, 6836 male) patients was evaluated retrospectively in this study. Patients’ clinical and demographic data were recorded using the Hospital Information System.

Results: Left renal vein variations were detected in 314 (2.54%) of the 12,341 patients within the study. Of the 314 cases found to have LRV variations, 227 (1.84%) had RLRV, and 87 (0.70%) had CLRV. There was no statistical difference in total LRV variations (p = 0.083) and CLRV variation (p = 0.96) groups in terms of gender. However, the RLRV variation was found to be 1.32 times higher in males than in females (p = 0.039). Of the 314 patients with LRV variations, 73 (23.2%) had any sort of concomitant malignancy.

Conclusions: A high incidence of malignancy was detected in patients with LRV variations. Of the LRV variations, RLRV variation is more common than CLRV variation. The presence of total LRV variations and CLRV variations is not associated with gender; whereas the presence of RLRV variation is more common in males.

Abstract

Background: Left renal vein (LRV) variations occur in 0.8–10.2% of the population. The most common LRV variations are retroaortic left renal vein (RLRV) and circumaortic left renal vein (CLRV). The purpose of this study is to determine the frequency of LRV variations in a large series on computed tomography (CT) and to investigate the association between LRV and malignancy development.

Materials and methods: Between January 2015 and January 2017, an abdominal CT examination of 12,341 (5505 female, 6836 male) patients was evaluated retrospectively in this study. Patients’ clinical and demographic data were recorded using the Hospital Information System.

Results: Left renal vein variations were detected in 314 (2.54%) of the 12,341 patients within the study. Of the 314 cases found to have LRV variations, 227 (1.84%) had RLRV, and 87 (0.70%) had CLRV. There was no statistical difference in total LRV variations (p = 0.083) and CLRV variation (p = 0.96) groups in terms of gender. However, the RLRV variation was found to be 1.32 times higher in males than in females (p = 0.039). Of the 314 patients with LRV variations, 73 (23.2%) had any sort of concomitant malignancy.

Conclusions: A high incidence of malignancy was detected in patients with LRV variations. Of the LRV variations, RLRV variation is more common than CLRV variation. The presence of total LRV variations and CLRV variations is not associated with gender; whereas the presence of RLRV variation is more common in males.

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Keywords

renal vein, variation, abnormality, malignancy, computed tomography, circumaortic, retroaortic

About this article
Title

Evaluation of the frequency of left renal vein variations in computed tomography and its relationship with cancer development

Journal

Folia Morphologica

Issue

Vol 79, No 4 (2020)

Article type

Original article

Pages

793-798

Published online

2019-12-20

DOI

10.5603/FM.a2019.0137

Pubmed

31886880

Bibliographic record

Folia Morphol 2020;79(4):793-798.

Keywords

renal vein
variation
abnormality
malignancy
computed tomography
circumaortic
retroaortic

Authors

T. Y. Kuzan
B. N. Kuzan
T. A. Telli
D. Tüney

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