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Interstitial cells of Cajal — systematic review
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Abstract
This paper reviews the distribution of interstitial cells of Cajal (ICC) in the human gastrointestinal (GI) tract, based on ultrastructural and immunohistochemical evidence. The distribution and morphology of ICC at each level of the normal GI tracts is addressed from the perspective of their functional significance. Alterations of ICC reported in as well as in GI stromal tumours are reviewed, with emphasis on the place of ICC in the pathophysiology of disease.
Abstract
This paper reviews the distribution of interstitial cells of Cajal (ICC) in the human gastrointestinal (GI) tract, based on ultrastructural and immunohistochemical evidence. The distribution and morphology of ICC at each level of the normal GI tracts is addressed from the perspective of their functional significance. Alterations of ICC reported in as well as in GI stromal tumours are reviewed, with emphasis on the place of ICC in the pathophysiology of disease.
Keywords
gallbladder, gallstone disease, anatomy, interstitial cells of Cajal, telocytes
About this articleTitle
Interstitial cells of Cajal — systematic review
Journal
Issue
Article type
Review article
Pages
281-286
Published online
2016-01-19
Page views
4107
Article views/downloads
4255
DOI
Pubmed
Bibliographic record
Folia Morphol 2016;75(3):281-286.
Keywords
gallbladder
gallstone disease
anatomy
interstitial cells of Cajal
telocytes
Authors
A. Pasternak
M. Szura
K. Gil
A. Matyja
