open access

Vol 63, No 1 (2004)
Short Communications
Published online: 2003-12-03
Submitted: 2012-02-06
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Green tea as an antioxidant which protects against alcohol induced injury in rats - a histopathological examination

Marek Baltaziak, Elżbieta Skrzydlewska, Artur Sulik, Waldemar Famulski, Mariusz Koda
Folia Morphol 2004;63(1):123-126.

open access

Vol 63, No 1 (2004)
Short Communications
Published online: 2003-12-03
Submitted: 2012-02-06

Abstract

Our study with animal models was designed to test the hypothesis that green tea protects against chronic (over 4 weeks) alcohol induced liver injury in rats. The research was conducted on Wistar male rats divided into 4 research groups: I - received the Libera-De Carli control diet (L-DC), II - received (L-DC) and green tea, III - received (L-DC) and ethanol and IV - received (L-DC), green tea and ethanol. When comparing groups I and II we saw less intensive steatosis in group II than in group I, which can suggest that green tea may affect the accumulation of fat in the hepatocytes and protect them against steatosis and disruption. In III, the ethanol group, the steatosis of the liver increased considerably and the green tea which was given with ethanol in group IV did not halt this, as in group IV we also observed intensive steatosis in the liver. From this data we conclude that green tea has an important, although not fully understood role in preventing liver injury.

Abstract

Our study with animal models was designed to test the hypothesis that green tea protects against chronic (over 4 weeks) alcohol induced liver injury in rats. The research was conducted on Wistar male rats divided into 4 research groups: I - received the Libera-De Carli control diet (L-DC), II - received (L-DC) and green tea, III - received (L-DC) and ethanol and IV - received (L-DC), green tea and ethanol. When comparing groups I and II we saw less intensive steatosis in group II than in group I, which can suggest that green tea may affect the accumulation of fat in the hepatocytes and protect them against steatosis and disruption. In III, the ethanol group, the steatosis of the liver increased considerably and the green tea which was given with ethanol in group IV did not halt this, as in group IV we also observed intensive steatosis in the liver. From this data we conclude that green tea has an important, although not fully understood role in preventing liver injury.
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Keywords

rats; liver; ethanol; green tea; steatosis; histopathology

About this article
Title

Green tea as an antioxidant which protects against alcohol induced injury in rats - a histopathological examination

Journal

Folia Morphologica

Issue

Vol 63, No 1 (2004)

Pages

123-126

Published online

2003-12-03

Bibliographic record

Folia Morphol 2004;63(1):123-126.

Keywords

rats
liver
ethanol
green tea
steatosis
histopathology

Authors

Marek Baltaziak
Elżbieta Skrzydlewska
Artur Sulik
Waldemar Famulski
Mariusz Koda

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