open access

Vol 63, No 1 (2004)
SHORT COMMUNICATIONS
Published online: 2003-12-03
Submitted: 2012-02-06
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An evaluation of Ki-67 and PCNA expression in conjunctival and eyelid tumours

Joanna Reszeć, Luiza Kańczuga-Koda, Mariola Sulkowska, Mariusz Koda, Jacek Cylwik, Małgorzata Barwijuk-Machała, Stanisław Sulkowski
Folia Morphol 2004;63(1):95-98.

open access

Vol 63, No 1 (2004)
SHORT COMMUNICATIONS
Published online: 2003-12-03
Submitted: 2012-02-06

Abstract

The aim of our study was an evaluation of the expression of cell proliferation markers (PCNA and Ki-67) in conjunctival and eyelid papillomas and squamous and basal cell cancers. A series of 9 cases of squamous cell cancer (SCC), 15 cases of basal cell cancer (BCC) and 43 cases of squamous cell papilloma (SCP) were assessed using the immunohistochemical method with monoclonal antibodies. PCNA overexpression was observed in 100% of SCP, in 88.8% of SCC and in 100% of BCC cases. Ki-67 overexpression was seen in 32.5% of cases of SCP, in 22.2% of SCC and in 66.6% of BCC. The results showed that an evaluation of Ki-67 expression is the most valuable cell proliferation marker.

Abstract

The aim of our study was an evaluation of the expression of cell proliferation markers (PCNA and Ki-67) in conjunctival and eyelid papillomas and squamous and basal cell cancers. A series of 9 cases of squamous cell cancer (SCC), 15 cases of basal cell cancer (BCC) and 43 cases of squamous cell papilloma (SCP) were assessed using the immunohistochemical method with monoclonal antibodies. PCNA overexpression was observed in 100% of SCP, in 88.8% of SCC and in 100% of BCC cases. Ki-67 overexpression was seen in 32.5% of cases of SCP, in 22.2% of SCC and in 66.6% of BCC. The results showed that an evaluation of Ki-67 expression is the most valuable cell proliferation marker.
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Keywords

Ki-67; PCNA; papilloma; squamous cell cancer; basal cell cancer of conjunctiva and eyelid

About this article
Title

An evaluation of Ki-67 and PCNA expression in conjunctival and eyelid tumours

Journal

Folia Morphologica

Issue

Vol 63, No 1 (2004)

Pages

95-98

Published online

2003-12-03

Bibliographic record

Folia Morphol 2004;63(1):95-98.

Keywords

Ki-67
PCNA
papilloma
squamous cell cancer
basal cell cancer of conjunctiva and eyelid

Authors

Joanna Reszeć
Luiza Kańczuga-Koda
Mariola Sulkowska
Mariusz Koda
Jacek Cylwik
Małgorzata Barwijuk-Machała
Stanisław Sulkowski

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