Multimedialna platforma wiedzy medycznej Internetowa Księgarnia Medyczna Kalendarium Konferencji
Folia Morphologica
MENU
Shortcuts Submit an article Author Guidelines (new) Ahead Of Print Reviewers 2022

open access

Vol 63, No 1 (2004)
Short communication
Submitted: 2012-02-06
Published online: 2003-12-03
View PDF Download PDF file
Get Citation

Dactinomycin-induced veno-occlusive disease in rats. The hepatoprotective action of amifostine. Evaluation in a light and electron microscope

Halina Borowska, Ewa Arciszewska, Piotr Czauderna, Bogusław Sawicki
Folia Morphol 2004;63(1):91-93.

open access

Vol 63, No 1 (2004)
SHORT COMMUNICATIONS
Submitted: 2012-02-06
Published online: 2003-12-03

Abstract

The purpose of the study was to draw upan experimental model of hepatic veno-occlusive disease (VOD) induced by dactinomycin (ACT) and to investigate the possible hepatoprotective effects of Ethyol (amifostine). Pathological changes corresponding to a VOD picture of varying intensification were found in the liver samples obtained from all the rats receiving ACT. Amifostine appears to act protectively to liver changes caused by dactinomycin.

Abstract

The purpose of the study was to draw upan experimental model of hepatic veno-occlusive disease (VOD) induced by dactinomycin (ACT) and to investigate the possible hepatoprotective effects of Ethyol (amifostine). Pathological changes corresponding to a VOD picture of varying intensification were found in the liver samples obtained from all the rats receiving ACT. Amifostine appears to act protectively to liver changes caused by dactinomycin.

Full Text:

View PDF Download PDF file
Get Citation

Keywords

veno-occlusive liver disease (VOD); ethyol (amifostine); dactinomycin (ACT)

About this article
Title

Dactinomycin-induced veno-occlusive disease in rats. The hepatoprotective action of amifostine. Evaluation in a light and electron microscope

Journal

Folia Morphologica

Issue

Vol 63, No 1 (2004)

Article type

Short communication

Pages

91-93

Published online

2003-12-03

Page views

561

Article views/downloads

1164

Bibliographic record

Folia Morphol 2004;63(1):91-93.

Keywords

veno-occlusive liver disease (VOD)
ethyol (amifostine)
dactinomycin (ACT)

Authors

Halina Borowska
Ewa Arciszewska
Piotr Czauderna
Bogusław Sawicki

Regulations

Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

By VM Media Group sp. z o.o., Grupa Via Medica, Świętokrzyska 73, 80–180 Gdańsk, Poland

tel.: +48 58 320 94 94, faks: +48 58 320 94 60, e-mail: viamedica@viamedica.pl