open access

Vol 63, No 3 (2004)
Short communication
Submitted: 2012-02-06
Published online: 2004-06-04
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Proliferation and apoptosis in the guinea pig adrenal cortex during postnatal development

D Kaczmarczyk, BL Kmieć, M Daczewska, KB Kmieć
Folia Morphol 2004;63(3):333-335.

open access

Vol 63, No 3 (2004)
SHORT COMMUNICATIONS
Submitted: 2012-02-06
Published online: 2004-06-04

Abstract

The aim of the study was to determine the relation between involution of the FZ and the proliferation and apoptosis of the adrenal cortex cells.
The study was carried out with adrenal glands from guinea pigs aged 1, 3, 9, 14, 21, 35 and 90 days. Paraffin slices were stained with Mayer haematoxylin and eosin and with acid fuchsin. For the immunohistochemical reaction the Anti -PCNA Clone PC10 (Dako) was used. Apoptosis evaluation was performed with use of the TUNEL method (Roche).
The results support the theory of involution of the FZ cells realised mainly by way of apoptosis. Analysis of the distribution and number of PCNA-positive cells in the adrenal cortex on subsequent days of PD may also back up the migration theory of renewal of the adrenal cortex cells.

Abstract

The aim of the study was to determine the relation between involution of the FZ and the proliferation and apoptosis of the adrenal cortex cells.
The study was carried out with adrenal glands from guinea pigs aged 1, 3, 9, 14, 21, 35 and 90 days. Paraffin slices were stained with Mayer haematoxylin and eosin and with acid fuchsin. For the immunohistochemical reaction the Anti -PCNA Clone PC10 (Dako) was used. Apoptosis evaluation was performed with use of the TUNEL method (Roche).
The results support the theory of involution of the FZ cells realised mainly by way of apoptosis. Analysis of the distribution and number of PCNA-positive cells in the adrenal cortex on subsequent days of PD may also back up the migration theory of renewal of the adrenal cortex cells.
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Keywords

adrenal gland; foetal zone; PCNA

About this article
Title

Proliferation and apoptosis in the guinea pig adrenal cortex during postnatal development

Journal

Folia Morphologica

Issue

Vol 63, No 3 (2004)

Article type

Short communication

Pages

333-335

Published online

2004-06-04

Page views

461

Article views/downloads

1748

Bibliographic record

Folia Morphol 2004;63(3):333-335.

Keywords

adrenal gland
foetal zone
PCNA

Authors

D Kaczmarczyk
BL Kmieć
M Daczewska
KB Kmieć

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