open access

Vol 67, No 1 (2008)
ORIGINAL ARTICLES
Published online: 2007-12-03
Submitted: 2012-02-06
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The structure of acquired aural cholesteatoma as revealed by scanning electron microscopy

A.J. Miodoński, J.A. Litwin, J. Składzień, K. Zagórska-Swieży
Folia Morphol 2008;67(1):1-5.

open access

Vol 67, No 1 (2008)
ORIGINAL ARTICLES
Published online: 2007-12-03
Submitted: 2012-02-06

Abstract

The structural features of cells, their surfaces and the extracellular matrix were investigated in acquired aural cholesteatoma. Cholesteatomas surgically removed from 30 patients were examined by a scanning electron microscope (SEM). The predominant part of a cholesteatoma was composed of stratified squamous epithelium, showing extensive chaotic desquamation. The surface sculpture of the keratinocytes and corneocytes varied from parallel ridges, irregular microplicae and mirovilli, to flat grooves and pits and a completely smooth surface. Sheetlike lamellar structures, probably representing an intercellular lipid-forming permeability barrier, were also observed. Small crystals located in the perimatrix were observed in one case.
According to the SEM observations, cholesteatoma epithelium is characterised by abnormal and uncoordinated keratinisation, with a predominance of the advanced stages of the process. Folia Morphol 2008; 67: 8–12)

Abstract

The structural features of cells, their surfaces and the extracellular matrix were investigated in acquired aural cholesteatoma. Cholesteatomas surgically removed from 30 patients were examined by a scanning electron microscope (SEM). The predominant part of a cholesteatoma was composed of stratified squamous epithelium, showing extensive chaotic desquamation. The surface sculpture of the keratinocytes and corneocytes varied from parallel ridges, irregular microplicae and mirovilli, to flat grooves and pits and a completely smooth surface. Sheetlike lamellar structures, probably representing an intercellular lipid-forming permeability barrier, were also observed. Small crystals located in the perimatrix were observed in one case.
According to the SEM observations, cholesteatoma epithelium is characterised by abnormal and uncoordinated keratinisation, with a predominance of the advanced stages of the process. Folia Morphol 2008; 67: 8–12)
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Keywords

epithelium; keratinisation; scanning electron microscopy

About this article
Title

The structure of acquired aural cholesteatoma as revealed by scanning electron microscopy

Journal

Folia Morphologica

Issue

Vol 67, No 1 (2008)

Pages

1-5

Published online

2007-12-03

Bibliographic record

Folia Morphol 2008;67(1):1-5.

Keywords

epithelium
keratinisation
scanning electron microscopy

Authors

A.J. Miodoński
J.A. Litwin
J. Składzień
K. Zagórska-Swieży

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