Vol 47, No 2 (2009)
Original paper
Published online: 2009-12-10

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Quantitative determination and localization of cathepsin D and its inhibitors.

Alina Minarowska, Alicja Karwowska, Marek Gacko
DOI: 10.2478/v10042-009-0073-4
Folia Histochem Cytobiol 2009;47(2):153-177.


A literature survey was performed of the methods of quantitative assessment of the activity and concentration of cathepsin D and its inhibitors. Usefulness of non-modified and modified proteins and synthetic peptides as measurement substrates was evaluated. The survey includes also chemical and immunochemical methods used to determine the distribution of cathepsin D and its inhibitors in cells and tissues.

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Folia Histochemica et Cytobiologica