Vol 47, No 2 (2009)
Original paper
Published online: 2009-12-10
Quantitative determination and localization of cathepsin D and its inhibitors.
DOI: 10.2478/v10042-009-0073-4
Folia Histochem Cytobiol 2009;47(2):153-177.
Abstract
A literature survey was performed of the methods of quantitative assessment of the activity and concentration of cathepsin D and its inhibitors. Usefulness of non-modified and modified proteins and synthetic peptides as measurement substrates was evaluated. The survey includes also chemical and immunochemical methods used to determine the distribution of cathepsin D and its inhibitors in cells and tissues.
