Tom 14, Nr 1 (2019)
Artykuł przeglądowy
Opublikowany online: 2018-09-05
Wyświetlenia strony
657
Wyświetlenia/pobrania artykułu
752
Nowe markery biologiczne w kardiologii — czy to właściwy trop?
Folia Cardiologica 2019;14(1):52-59.
Streszczenie
Istnieje wiele markerów oceny ryzyka chorób sercowo-naczyniowych (CVD). Wciąż poszukuje się nowych czułych i spe- cyficznych biomarkerów, które mogłyby pomóc w stratyfikacji ryzyka zarówno wśród populacji zdrowej, jak i obciążonej CVD. Galektyna 3 oraz białko ST-2 wydają się niezwykle obiecującymi wskaźnikami, niemniej potrzebne są dalsze ba- dania nad tymi cząsteczkami, aby poznać ich pełną wartość diagnostyczno-prognostyczną. W artykule zaprezentowano badania i publikacje przedstawiające możliwość wszechstronnego wykorzystania obu biomarkerów, zwłaszcza w cho- robie wieńcowej. Galektyna-3 oraz białko ST-2, dzięki związkowi z procesami włóknienia, mogą się okazać kluczowymi markerami u pacjentów z chorobą wieńcową oraz po zawale serca.
Słowa kluczowe: białko ST-2choroby układu sercowo-naczyniowegochoroba wieńcowagalektyna 3remodelingzawał serca
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