Tom 16, Nr 5 (2021)
Artykuł przeglądowy
Opublikowany online: 2021-10-31
Wyświetlenia strony
2944
Wyświetlenia/pobrania artykułu
582
Garlic for arterial hypertension and hypercholesterolaemia. Review of literature studies and clinical studies
12
, 1, 3, 4
, 1, 3, 4
DOI: 10.5603/FC.2021.0045
Folia Cardiologica 2021;16(5):296-302.
Streszczenie
Garlic is a widely known and widely used plant. Due to its taste, it is used in the preparation of many dishes. Garlic is also used in the treatment of bacterial, viral, fungal and parasitic infections. There are many chemical compounds in garlic, but those responsible for its health-promoting effect include, first of all, those containing sulfur. These compounds are characterized by many mechanisms of action, such as antioxidant, cardioprotective and anti-inflammatory effects. Many mechanisms of action of organosulfur compounds influencing the regulation of blood pressure and lipid metabolism have been demonstrated. Many clinical studies and meta-analyses are assessing the effect of garlic on blood pressure and lipid profile in various groups of patients in the literature. This article aims to present the current knowledge on the influence of garlic on blood pressure and lipid metabolism.
Słowa kluczowe: garlicblood pressurelipidsarterial hypertensionhypercholesterolemia
Referencje
- Niklas A, Flotyńska A, Puch-Walczak A, et al. WOBASZ II investigators. Prevalence, awareness, treatment and control of hypertension in the adult Polish population - Multi-center National Population Health Examination Surveys - WOBASZ studies. Arch Med Sci. 2018; 14(5): 951–961.
- Pająk A, Szafraniec K, Polak M, et al. WOBASZ Investigators. Changes in the prevalence, treatment, and control of hypercholesterolemia and other dyslipidemias over 10 years in Poland: the WOBASZ study. Pol Arch Med Wewn. 2016; 126(9): 642–652.
- Niklas A, Marcinkowska J, Kozela M, et al. Blood pressure and cholesterol control in patients with hypertension and hypercholesterolemia: the results from the Polish multicenter national health survey WOBASZ II. Pol Arch Intern Med. 2019; 129(12): 864–873.
- Surma S, Szyndler A, Narkiewicz K. Świadomość wybranych czynników ryzyka chorób układu sercowo-naczyniowego w populacji młodych osób. Choroby Serca i Naczyń. 2017; 14(4): 186–193.
- Surma S, Szyndler A, Narkiewicz K. Świadomość nadciśnienia tętniczego i innych czynników ryzyka chorób układu sercowo-naczyniowego w populacji osób dorosłych. Choroby Serca i Naczyń. 2018; 15(1): 14–22.
- Ndanuko RN, Tapsell LC, Charlton KE, et al. Dietary patterns and blood pressure in adults: a systematic review and meta-analysis of randomized controlled trials. Adv Nutr. 2016; 7(1): 76–89.
- Ge L, Sadeghirad B, Ball GDC, et al. Comparison of dietary macronutrient patterns of 14 popular named dietary programmes for weight and cardiovascular risk factor reduction in adults: systematic review and network meta-analysis of randomised trials. BMJ. 2020; 369: m696.
- Schoeneck M, Iggman D. The effects of foods on LDL cholesterol levels: a systematic review of the accumulated evidence from systematic reviews and meta-analyses of randomized controlled trials. Nutr Metab Cardiovasc Dis. 2021; 31(5): 1325–1338.
- Bayan L, Koulivand PH, Gorji A. Garlic: a review of potential therapeutic effects. Avicenna J Phytomed. 2014; 4(1): 1–14.
- Shang Ao, Cao SY, Xu XY, et al. Bioactive compounds and biological functions of garlic (Allium sativum L.). Foods. 2019; 8(7): 246.
- Ribeiro M, Alvarenga L, Cardozo LF, et al. From the distinctive smell to therapeutic effects: garlic for cardiovascular, hepatic, gut, diabetes and chronic kidney disease. Clin Nutr. 2021; 40(7): 4807–4819.
- Kopec A, Piatkowska E, Leszczynska T, et al. Healthy properties of garlic. Curr Nutr Food Sci. 2013; 9(1): 59–64.
- Rybczyńska K, Gaweł-Bęben K, Surma S, Gmiński J. Wpływ ekstraktów z różnych odmian czosnku na ekspresję metaloproteaz ADAM w ludzkich komórkach śródbłonka in vitro. In: Karkowska M, Gustaw W. ed. Trendy w żywieniu człowieka. Wydawnictwo Naukowe, Polskie Wydawnictwo Technologii Żywności, Kraków 2015: 279–287.
- Matysiak M, Gaweł-Bęben K, Rybczyńska K, et al. [Comparing selected biological properties of garlic (Allium sativum L.) from Poland and China] [Article in Polish]. Zywnosc.Nauka.Technologia.Jakosc/Food.Science.Technology.Quality. 2015; 21(99): 160–169.
- Matysiak M, Rybczyńska K, Gaweł-Bęben K, Surma S, Gmiński J. Antioxidant properities of garlic verieties. 5th International Young Scientists Conference "Human - Nutrition - Environment". Abstract book. Rzeszów 2014: 207–208.
- Gaweł-Bęben K, Surma S. Antosiewicz B. Binduga U. Wołowiec S, Gmiński J. Oblicza różnych odmian czosnku. XII Ogólnopolska Konferencja naukowa „Nowoczesne trendy w kosmetologii i dietetyce”. Książka streszczeń. Poznań 2013: 30–31.
- Borghi C, Cicero AFG. Nutraceuticals with a clinically detectable blood pressure-lowering effect: a review of available randomized clinical trials and their meta-analyses. Br J Clin Pharmacol. 2017; 83(1): 163–171.
- Hosseini A, Hosseinzadeh H. A review on the effects of Allium sativum (garlic) in metabolic syndrome. J Endocrinol Invest. 2015; 38(11): 1147–1157.
- Sobenin IA, Myasoedova VA, Iltchuk MI, et al. Therapeutic effects of garlic in cardiovascular atherosclerotic disease. Chin J Nat Med. 2019; 17(10): 721–728.
- Lin MC, Wang EJ, Lee C, et al. Garlic inhibits microsomal triglyceride transfer protein gene expression in human liver and intestinal cell lines and in rat intestine. J Nutr. 2002; 132(6): 1165–1168.
- Sun S, Lulla A, Sioda M, et al. Gut microbiota composition and blood pressure. Hypertension. 2019; 73(5): 998–1006.
- Liu J, Zhang D, Guo Y, et al. The effect of Lactobacillus consumption on human blood pressure: a systematic review and meta-analysis of randomized controlled trials. Complement Ther Med. 2020; 54: 102547.
- Ried K. Garlic lowers blood pressure in hypertensive subjects, improves arterial stiffness and gut microbiota: A review and meta-analysis. Exp Ther Med. 2020; 19(2): 1472–1478.
- Hoglund KB, Barnett BK, Watson SA, et al. Activity of bioactive garlic compounds on the oral microbiome: a literature review. Gen Dent. 2020; 68(3): 27–33.
- Bakri IM, Douglas CWI. Inhibitory effect of garlic extract on oral bacteria. Arch Oral Biol. 2005; 50(7): 645–651.
- Surma S, Romańczyk M, Witalińska-Łabuzek J, et al. Periodontitis, blood pressure, and the risk and control of arterial hypertension: epidemiological, clinical, and pathophysiological aspects — review of the literature and clinical trials. Curr Hypertens Rep. 2021; 23(5): 27.
- Mulawarman R, Trifitriana M, Felani M, et al. 13. Garlic effect on reduce blood pressure and cholesterol in patients with and without hypertension: a systematic review and meta-analysis of randomized controlled trials. J Hypertens. 2021; 39(Suppl 2): e4.
- Ried K. Garlic lowers blood pressure in hypertensive individuals, regulates serum cholesterol, and stimulates immunity: an updated meta-analysis and review. J Nutr. 2016; 146(2): 389S–396S.
- Rohner A, Ried K, Sobenin IA, et al. A systematic review and metaanalysis on the effects of garlic preparations on blood pressure in individuals with hypertension. Am J Hypertens. 2015; 28(3): 414–423.
- Wang HP, Yang J, Qin LQ, et al. Effect of garlic on blood pressure: a meta-analysis. J Clin Hypertens (Greenwich). 2015; 17(3): 223–231.
- Xiong XJ, Wang PQ, Li SJ, et al. Garlic for hypertension: a systematic review and meta-analysis of randomized controlled trials. Phytomedicine. 2015; 22(3): 352–361.
- Kwak JS, Kim JiY, Paek JuE, et al. Garlic powder intake and cardiovascular risk factors: a meta-analysis of randomized controlled clinical trials. Nutr Res Pract. 2014; 8(6): 644–654.
- Gyawali D, Vohra R, Orme-Johnson D, et al. A systematic review and meta-analysis of ayurvedic herbal preparations for hypercholesterolemia. Medicina (Kaunas). 2021; 57(6).
- Shabani E, Sayemiri K, Mohammadpour M. The effect of garlic on lipid profile and glucose parameters in diabetic patients: A systematic review and meta-analysis. Prim Care Diabetes. 2019; 13(1): 28–42.
- Sun YE, Wang W, Qin J. Anti-hyperlipidemia of garlic by reducing the level of total cholesterol and low-density lipoprotein: A meta-analysis. Medicine (Baltimore). 2018; 97(18): e0255.
- Sahebkar A, Serban C, Ursoniu S, et al. Effect of garlic on plasma lipoprotein(a) concentrations: a systematic review and meta-analysis of randomized controlled clinical trials. Nutrition. 2016; 32(1): 33–40.
- Ried K, Toben C, Fakler P. Effect of garlic on serum lipids: an updated meta-analysis. Nutr Rev. 2013; 71(5): 282–299.
- Zeng T, Guo FF, Zhang CL, et al. A meta-analysis of randomized, double-blind, placebo-controlled trials for the effects of garlic on serum lipid profiles. J Sci Food Agric. 2012; 92(9): 1892–1902.
- Schoeneck M, Iggman D. The effects of foods on LDL cholesterol levels: a systematic review of the accumulated evidence from systematic reviews and meta-analyses of randomized controlled trials. Nutr Metab Cardiovasc Dis. 2021; 31(5): 1325–1338.
- Wlosinska M, Nilsson AC, Hlebowicz J, et al. The effect of aged garlic extract on the atherosclerotic process — a randomized double-blind placebo-controlled trial. BMC Complement Med Ther. 2020; 20(1): 132.
- Szymański FM, Mickiewicz A, Dzida G, et al. Leczenie dyslipidemii w Polsce — interdyscyplinarne stanowisko grupy ekspertów wsparte przez Sekcję Farmakoterapii Sercowo-Naczyniowej Polskiego Towarzystwa Kardiologicznego. IV Deklaracja Sopocka. Choroby Serca i Naczyń. 2021.
- Banach M, Burchardt P, Chlebus K, et al. PoLA/CFPiP/PCS/PSLD/PSD/PSH guidelines on the diagnosis and tehrapy of lipid disorders in Poland. Arch Med Sci. 2021; 17(6): in press.
