open access

Vol 14, No 6 (2019)
Original Papers
Published online: 2019-12-31
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Evaluation of autonomic nervous system function with heart rate variability analysis in preterm infants — a literature review

Marta Makowska, Jakub Sławomir Gąsior, Wacław Kochman, Bożena Werner, Bożena Werner
DOI: 10.5603/FC.2019.0110
·
Folia Cardiologica 2019;14(6):545-555.

open access

Vol 14, No 6 (2019)
Original Papers
Published online: 2019-12-31

Abstract

Introduction. Preterm birth, despite the constant development of medicine and improved perinatal care, remains one of the greatest challenges in obstetrics. A prematurely born child presents a number of disorders, including abnormalities of the autonomic nervous system (ANS), which affect, among others, the functioning of the heart muscle. One method used to assess the influence of ANS activity on heart rate is the analysis of heart rate variability (HRV), which gives an indirect picture of its influence on the ability to adapt the systolic function of the ANS to external stimuli.

The aim of this study was to evaluate the activity of the autonomic nervous system on the basis of values of HRV parameters in children born prematurely on the basis of a literature review.

Material and methods. The literature review was carried out in accordance with PRISMA statement. Medical databases were reviewed including MEDLINE/PubMed, ProQest, PEDro, Cochrane, and Embase using the key phrases: ‘heart rate variability’ in combination with ‘preterm infants’.

Results. Between 1997 and 2018, 26 publications meeting the inclusion criteria were identified, of which 15 were selected for detailed analysis. Selected time and frequency domain HRV parameters were analysed in the review.

Conclusions. Preterm infants are susceptible to heart rhythm control disorders by the autonomic nervous system expressed by rapid and temporary changes in heart rate. They have higher heart rate and selected HRV parameters, suggesting a dominance of sympathetic activity in heart rate control. In addition, existing studies are not sufficiently systematic to be able to be compared to each other. Therefore, this subject requires further research.

Abstract

Introduction. Preterm birth, despite the constant development of medicine and improved perinatal care, remains one of the greatest challenges in obstetrics. A prematurely born child presents a number of disorders, including abnormalities of the autonomic nervous system (ANS), which affect, among others, the functioning of the heart muscle. One method used to assess the influence of ANS activity on heart rate is the analysis of heart rate variability (HRV), which gives an indirect picture of its influence on the ability to adapt the systolic function of the ANS to external stimuli.

The aim of this study was to evaluate the activity of the autonomic nervous system on the basis of values of HRV parameters in children born prematurely on the basis of a literature review.

Material and methods. The literature review was carried out in accordance with PRISMA statement. Medical databases were reviewed including MEDLINE/PubMed, ProQest, PEDro, Cochrane, and Embase using the key phrases: ‘heart rate variability’ in combination with ‘preterm infants’.

Results. Between 1997 and 2018, 26 publications meeting the inclusion criteria were identified, of which 15 were selected for detailed analysis. Selected time and frequency domain HRV parameters were analysed in the review.

Conclusions. Preterm infants are susceptible to heart rhythm control disorders by the autonomic nervous system expressed by rapid and temporary changes in heart rate. They have higher heart rate and selected HRV parameters, suggesting a dominance of sympathetic activity in heart rate control. In addition, existing studies are not sufficiently systematic to be able to be compared to each other. Therefore, this subject requires further research.

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Keywords

heart rate variability, autonomic nervous system, prematurity

About this article
Title

Evaluation of autonomic nervous system function with heart rate variability analysis in preterm infants — a literature review

Journal

Folia Cardiologica

Issue

Vol 14, No 6 (2019)

Pages

545-555

Published online

2019-12-31

DOI

10.5603/FC.2019.0110

Bibliographic record

Folia Cardiologica 2019;14(6):545-555.

Keywords

heart rate variability
autonomic nervous system
prematurity

Authors

Marta Makowska
Jakub Sławomir Gąsior
Wacław Kochman
Bożena Werner
Bożena Werner

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