open access

Vol 12, No 5 (2017)
Young Cardiology
Published online: 2017-11-22
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Prognostic utility of 99mTc-MIBI single-photon emission computed tomography (SPECT) in post-myocardial infarction patients

Ewelina Kowalczyk, Dominika Filipiak-Strzecka, Piotr Hamala, Nina Śmiech, Jarosław D. Kasprzak, Jacek Kuśmierek, Anna Płachcińska, Piotr Lipiec
DOI: 10.5603/FC.2017.0084
·
Folia Cardiologica 2017;12(5):447-452.

open access

Vol 12, No 5 (2017)
Young Cardiology
Published online: 2017-11-22

Abstract

Introduction. Data describing prognostic utility of SPECT (single-photon emission computed tomography) among patients with history of myocardial infarction (MI) is scarce. We aimed to compare prognostic value of SPECT scans in patients with vs. without history of myocardial infarction (MI) prior to perfusion imaging. Material and methods. 151 consecutive patients with history of myocardial infarction, who underwent exercise 99mTc-MIBI SPECT examination were enrolled in the study (group 1). Next, based on clinical and demographic baseline characteristics, SPECT result and duration of follow-up period, a matching control subgroup (group 2) of 151 patients without history of MI was formed. During a mean follow-up of 60 ± 15 months in group 1 and a mean follow-up of 60 ± 13.5 months in group 2, we analyzed prevalence of cardiovascular events rates (cardiac deaths, myocardial infarctions and cardiac revascularizations). Results. We observed the following rates of cardiac deaths, myocardial infarctions and cardiac revascularizations: 4%, 15% and 26%, respectively in group 1 and 1%, 13% and 17%, respectively in group 2. In patients without history of MI (group 2) presence of mixed perfusion defects on SPECT was associated with significantly higher rate of myocardial infarctions (p = 0.05), hospitalizatons (p = 0.0001) and revascularizations (p = 0.0002). Fixed perfusion defects were associated with significantly higher occurrence of deaths (p = 0.012) and hospitalizations (p = 0.02), but not myocardial infarctions (p = 0.52) or cardiac revascularizations (p = 0.10). In contrast, among patients with history of MI (group 1) there was no statistically significant relationship between any type of perfusion defects and cardiovascular events. Conclusions. Long term follow-up demonstrates that prognostic value of 99mTc-MIBI SPECT is different in patients with and without history of MI.

Abstract

Introduction. Data describing prognostic utility of SPECT (single-photon emission computed tomography) among patients with history of myocardial infarction (MI) is scarce. We aimed to compare prognostic value of SPECT scans in patients with vs. without history of myocardial infarction (MI) prior to perfusion imaging. Material and methods. 151 consecutive patients with history of myocardial infarction, who underwent exercise 99mTc-MIBI SPECT examination were enrolled in the study (group 1). Next, based on clinical and demographic baseline characteristics, SPECT result and duration of follow-up period, a matching control subgroup (group 2) of 151 patients without history of MI was formed. During a mean follow-up of 60 ± 15 months in group 1 and a mean follow-up of 60 ± 13.5 months in group 2, we analyzed prevalence of cardiovascular events rates (cardiac deaths, myocardial infarctions and cardiac revascularizations). Results. We observed the following rates of cardiac deaths, myocardial infarctions and cardiac revascularizations: 4%, 15% and 26%, respectively in group 1 and 1%, 13% and 17%, respectively in group 2. In patients without history of MI (group 2) presence of mixed perfusion defects on SPECT was associated with significantly higher rate of myocardial infarctions (p = 0.05), hospitalizatons (p = 0.0001) and revascularizations (p = 0.0002). Fixed perfusion defects were associated with significantly higher occurrence of deaths (p = 0.012) and hospitalizations (p = 0.02), but not myocardial infarctions (p = 0.52) or cardiac revascularizations (p = 0.10). In contrast, among patients with history of MI (group 1) there was no statistically significant relationship between any type of perfusion defects and cardiovascular events. Conclusions. Long term follow-up demonstrates that prognostic value of 99mTc-MIBI SPECT is different in patients with and without history of MI.
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Keywords

myocardial infarction, prognosis, myocardial perfusion, SPECT

About this article
Title

Prognostic utility of 99mTc-MIBI single-photon emission computed tomography (SPECT) in post-myocardial infarction patients

Journal

Folia Cardiologica

Issue

Vol 12, No 5 (2017)

Pages

447-452

Published online

2017-11-22

DOI

10.5603/FC.2017.0084

Bibliographic record

Folia Cardiologica 2017;12(5):447-452.

Keywords

myocardial infarction
prognosis
myocardial perfusion
SPECT

Authors

Ewelina Kowalczyk
Dominika Filipiak-Strzecka
Piotr Hamala
Nina Śmiech
Jarosław D. Kasprzak
Jacek Kuśmierek
Anna Płachcińska
Piotr Lipiec

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