Vol 14, No 4 (2019)
Review paper
Published online: 2019-09-06
Immune system and hypertension
12
, 13, 124
, 13, 124
DOI: 10.5603/FC.2019.0094
Folia Cardiologica 2019;14(4):363-367.
Abstract
Hypertension is a very common disorder. It is a major risk factor of myocardial infarction, heart failure, stroke and renal failure. It is well known that the immune system also contributes to this disease. Numerous investigations have demonstrated that lymphocytes are important participants in the development of hypertension and consequent end-organ damage. They produce different cytokines such as tumor necrosis factor α, interferon γ, and interleukin 6 that lead to the development of hypertension. On the other hand, they are also the source of anti-inflammatory interleukin 10. A better knowledge of immunology would lead to the discovery of new therapeutic interventions and more successful treatment of our patients.
Keywords: hypertensionimmune systemlymphocytes
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