open access

Vol 11, No 3 (2016)
Review Papers
Published online: 2016-07-13
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Serelaxin and its organ protective activity in acute heart failure

Joanna Berner, Małgorzata Lelonek
DOI: 10.5603/FC.2016.0030
·
Folia Cardiologica 2016;11(3):194-201.

open access

Vol 11, No 3 (2016)
Review Papers
Published online: 2016-07-13

Abstract

Acute heart failure (AHF) is the reason of 80% of hospitalizations due to heart failure. It is known to be the important clinical problem because of frequent rehospitalizations and serious prognosis for the patient. The therapeutic goals of AHF include, among others: limitation of clinical symptoms, stabilization of the patient’s condition, optimalization of therapy and limitation of mortality and rehospitalization’s rate. Previously known therapeutic methods do not provide the complex implementation of the therapeutic goals. There are high hopes associated with serelaxin, which has a number of beneficial effects on heart, kidneys and liver and improves 180-days prognosis, what has been proven in wide analysis of the RELAX-AHF trial. We present the actual state of knowledge upon the beneficial effects of serelaxin in AHF with particular emphasis on its protective effect on vital organs.

Abstract

Acute heart failure (AHF) is the reason of 80% of hospitalizations due to heart failure. It is known to be the important clinical problem because of frequent rehospitalizations and serious prognosis for the patient. The therapeutic goals of AHF include, among others: limitation of clinical symptoms, stabilization of the patient’s condition, optimalization of therapy and limitation of mortality and rehospitalization’s rate. Previously known therapeutic methods do not provide the complex implementation of the therapeutic goals. There are high hopes associated with serelaxin, which has a number of beneficial effects on heart, kidneys and liver and improves 180-days prognosis, what has been proven in wide analysis of the RELAX-AHF trial. We present the actual state of knowledge upon the beneficial effects of serelaxin in AHF with particular emphasis on its protective effect on vital organs.

Get Citation

Keywords

serelaxin; acute heart failure

About this article
Title

Serelaxin and its organ protective activity in acute heart failure

Journal

Folia Cardiologica

Issue

Vol 11, No 3 (2016)

Pages

194-201

Published online

2016-07-13

DOI

10.5603/FC.2016.0030

Bibliographic record

Folia Cardiologica 2016;11(3):194-201.

Keywords

serelaxin
acute heart failure

Authors

Joanna Berner
Małgorzata Lelonek

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