open access

Vol 9, No 4 (2014)
Young Cardiology
Published online: 2014-12-22
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Clinical characteristics of hypertensive octogenarians based on single-centre data analysis

Łukasz Dobaj, Iwona Gorczyca-Michta, Maciej Krzysztof Kluk, Paweł Salwa, Ewa Tomasik, Katarzyna Dziubek, Beata Wożakowska-Kapłon
Folia Cardiologica 2014;9(4):346-351.

open access

Vol 9, No 4 (2014)
Young Cardiology
Published online: 2014-12-22

Abstract

Introduction. Arterial hypertension is one of the most common cardiovascular diseases in octogenarians. The aim of the study was clinical characteristics of patients with arterial hypertension over 80 years-old.

Material and methods. The study group consisted of 2512 hypertensive patients in mean age of 68.28 ± 11.15 years- -old, including group 1: 2148 patients in age up to 80 years-old (85.51%) and group 2: 364 patients over 80 years-old (14.49%). Clinical data was analysed including comorbidities, laboratory results and echocardiographic indices.

Results. Persistent atrial fibrillation was more frequent in group 1 (10.3% vs. 2.5%), while in group 2 permanent atrial fibrillation was observed (59.2% vs. 41.3%, p < 0.0001). There have been differences between group 1 and group 2 in frequencies of atrial fibrillation (24.4% vs. 44.5%, p < 0.0001), hyperlipidemia (30.8% vs. 18.7%, p < 0.0001), heart failure (34.5% vs. 55.0%, p < 0.0001), past non-fatal stroke (4.5% vs. 8.2%, p < 0.0023). No differences in stable angina, diabetes, hypertriglyceridemia, left ventricle hypertrophy, history of myocardial infarction, thyroid dysfunction have been noted. Patients in group 1 had higher values of hemoglobin (group 1 > 2, p < 0.0001), total cholesterol (group 1 > 2, p < 0.0001), LDL-cholesterol (group 1 > 2, p < 0.0004), triglycerides (group 1 > 2, p = 0.0003), glycemia (group 1 > 2, p = 0.0142), urea (group 1 < 2, p < 0.0001), uric acid (group 1 < 2, p = 0.0034), creatinine clearance (group 1 > 2, p < 0.0001), potassium (group 1 > 2, p = 0.0482) but not left ventricle ejection fraction in comparison to group 2.

Conclusions. Atrial fibrillation, heart failure and stroke were more frequent in hypertensive octogenarians compared to younger patients. Heart failure in hypertensives was classified as diastolic irrespectively of age. Renal dysfunction was not dependent on age however it was more pronounced in octogenarians compared to younger patients.

Abstract

Introduction. Arterial hypertension is one of the most common cardiovascular diseases in octogenarians. The aim of the study was clinical characteristics of patients with arterial hypertension over 80 years-old.

Material and methods. The study group consisted of 2512 hypertensive patients in mean age of 68.28 ± 11.15 years- -old, including group 1: 2148 patients in age up to 80 years-old (85.51%) and group 2: 364 patients over 80 years-old (14.49%). Clinical data was analysed including comorbidities, laboratory results and echocardiographic indices.

Results. Persistent atrial fibrillation was more frequent in group 1 (10.3% vs. 2.5%), while in group 2 permanent atrial fibrillation was observed (59.2% vs. 41.3%, p < 0.0001). There have been differences between group 1 and group 2 in frequencies of atrial fibrillation (24.4% vs. 44.5%, p < 0.0001), hyperlipidemia (30.8% vs. 18.7%, p < 0.0001), heart failure (34.5% vs. 55.0%, p < 0.0001), past non-fatal stroke (4.5% vs. 8.2%, p < 0.0023). No differences in stable angina, diabetes, hypertriglyceridemia, left ventricle hypertrophy, history of myocardial infarction, thyroid dysfunction have been noted. Patients in group 1 had higher values of hemoglobin (group 1 > 2, p < 0.0001), total cholesterol (group 1 > 2, p < 0.0001), LDL-cholesterol (group 1 > 2, p < 0.0004), triglycerides (group 1 > 2, p = 0.0003), glycemia (group 1 > 2, p = 0.0142), urea (group 1 < 2, p < 0.0001), uric acid (group 1 < 2, p = 0.0034), creatinine clearance (group 1 > 2, p < 0.0001), potassium (group 1 > 2, p = 0.0482) but not left ventricle ejection fraction in comparison to group 2.

Conclusions. Atrial fibrillation, heart failure and stroke were more frequent in hypertensive octogenarians compared to younger patients. Heart failure in hypertensives was classified as diastolic irrespectively of age. Renal dysfunction was not dependent on age however it was more pronounced in octogenarians compared to younger patients.

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Keywords

arterial hypertension, blood pressure, cardiovascular diseases, octogenarians, clinical characteristics

About this article
Title

Clinical characteristics of hypertensive octogenarians based on single-centre data analysis

Journal

Folia Cardiologica

Issue

Vol 9, No 4 (2014)

Pages

346-351

Published online

2014-12-22

Bibliographic record

Folia Cardiologica 2014;9(4):346-351.

Keywords

arterial hypertension
blood pressure
cardiovascular diseases
octogenarians
clinical characteristics

Authors

Łukasz Dobaj
Iwona Gorczyca-Michta
Maciej Krzysztof Kluk
Paweł Salwa
Ewa Tomasik
Katarzyna Dziubek
Beata Wożakowska-Kapłon

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