open access

Vol 9, No 3 (2014)
Young Cardiology
Published online: 2014-09-19
Get Citation

Impaired renal function in hospitalized patients with hypertension and type 2 diabetes

Paweł Salwa, Iwona Gorczyca-Michta, Maciej Kluk, Katarzyna Dziubek, Ewa Tomasik, Barbara Sosnowska-Pasiarska, Alicja Stępień-Wałek, Beata Wożakowska-Kapłon
Folia Cardiologica 2014;9(3):238-244.

open access

Vol 9, No 3 (2014)
Young Cardiology
Published online: 2014-09-19

Abstract

Introduction. Patients with hypertension and type 2 diabetes are a population characterized by a particularly high cardiovascular risk. Concomitant presence of these two diseases predisposes to the development of chronic kidney disease. The aim of the study was to evaluate renal function in patients with hypertension and type 2 diabetes, taking into account other cardiovascular risk factors and concomitant disease.

Material and methods. We performed a retrospective analysis of medical records of patients with hypertension andtype 2 diabetes hospitalized in a referral cardiac unit in 2009–2010. Glomerular filtration rate (GFR) was evaluated inthe study population. We evaluated the rates of atrial fibrillation, ischaemic heart disease, hyperuricaemia, and chronic heart failure in patients with normal and impaired renal function.

Results. We analyzed medical records of 635 patients who fulfilled the inclusion criteria. Impaired renal function definedas GFR < 60 mL/min/1.73 m2 was found in 56.2% (n = 357) of patients with hypertension and type 2 diabetes. Atrial fibrillation was significantly more common in patients with impaired renal function compared to those with normal GFR (142 vs. 52 patients; p < 0.0001). No significant differences in the rates of dyslipidaemia, previous stroke or myocardial infarction were found between the two groups. Severe heart failure (NYHA class III and IV) and hyperuricaemia weremore frequent in patients with GFR < 60 mL/min/1.73 m2.

Conclusions.

1) Impaired renal function was found in 56.2% of patients with hypertension and type 2 diabetes.

2) Among patients with hypertension and type 2 diabetes, atrial fibrillation was more frequent in patients with impaired renal function compared to those with normal GFR.

3) Among these patients, hyperuricaemia was seen more frequently in patients with GFR < 60 mL/min/1.73 m2 compared to those with normal GFR.

4) In a population with hypertensionand type 2 diabetes, advanced stages of heart failure (NYHA class III and IV) are more frequent in patients with impaired renal function compared to those with normal GFR.

Abstract

Introduction. Patients with hypertension and type 2 diabetes are a population characterized by a particularly high cardiovascular risk. Concomitant presence of these two diseases predisposes to the development of chronic kidney disease. The aim of the study was to evaluate renal function in patients with hypertension and type 2 diabetes, taking into account other cardiovascular risk factors and concomitant disease.

Material and methods. We performed a retrospective analysis of medical records of patients with hypertension andtype 2 diabetes hospitalized in a referral cardiac unit in 2009–2010. Glomerular filtration rate (GFR) was evaluated inthe study population. We evaluated the rates of atrial fibrillation, ischaemic heart disease, hyperuricaemia, and chronic heart failure in patients with normal and impaired renal function.

Results. We analyzed medical records of 635 patients who fulfilled the inclusion criteria. Impaired renal function definedas GFR < 60 mL/min/1.73 m2 was found in 56.2% (n = 357) of patients with hypertension and type 2 diabetes. Atrial fibrillation was significantly more common in patients with impaired renal function compared to those with normal GFR (142 vs. 52 patients; p < 0.0001). No significant differences in the rates of dyslipidaemia, previous stroke or myocardial infarction were found between the two groups. Severe heart failure (NYHA class III and IV) and hyperuricaemia weremore frequent in patients with GFR < 60 mL/min/1.73 m2.

Conclusions.

1) Impaired renal function was found in 56.2% of patients with hypertension and type 2 diabetes.

2) Among patients with hypertension and type 2 diabetes, atrial fibrillation was more frequent in patients with impaired renal function compared to those with normal GFR.

3) Among these patients, hyperuricaemia was seen more frequently in patients with GFR < 60 mL/min/1.73 m2 compared to those with normal GFR.

4) In a population with hypertensionand type 2 diabetes, advanced stages of heart failure (NYHA class III and IV) are more frequent in patients with impaired renal function compared to those with normal GFR.

Get Citation

Keywords

hypertension, diabetes, impaired renal function, glomerular filtration rate

About this article
Title

Impaired renal function in hospitalized patients with hypertension and type 2 diabetes

Journal

Folia Cardiologica

Issue

Vol 9, No 3 (2014)

Pages

238-244

Published online

2014-09-19

Bibliographic record

Folia Cardiologica 2014;9(3):238-244.

Keywords

hypertension
diabetes
impaired renal function
glomerular filtration rate

Authors

Paweł Salwa
Iwona Gorczyca-Michta
Maciej Kluk
Katarzyna Dziubek
Ewa Tomasik
Barbara Sosnowska-Pasiarska
Alicja Stępień-Wałek
Beata Wożakowska-Kapłon

Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

 

Wydawcą serwisu jest  "Via Medica sp. z o.o." sp.k., ul. Świętokrzyska 73, 80–180 Gdańsk

tel.:+48 58 320 94 94, faks:+48 58 320 94 60, e-mail:  viamedica@viamedica.pl