Stereotactic Radiosurgery in the Treatment of Ventricular Arrhythmia

Abstract

Stereotactic radiosurgery (SRS) is gaining recognition as a promising treatment modality for ventricular arrhythmias, particularly in patients for whom conventional therapies, such as pharmacological management and catheter ablation, have failed or are contraindicated. SRS employs precise irradiation targeting of the arrhythmogenic foci, which enables the selective ablation of pathological cardiac tissues while preserving surrounding healthy tissue. Clinical studies, such as SMART-VT, have shown encouraging results, demonstrating significant reductions in ventricular tachycardia episodes and confirming the safety profile of this therapeutic approach. Despite these promising findings, further studies are needed to involve larger, more diverse patient populations and extended follow-up periods to thoroughly evaluate the long-term efficacy and safety of this method. The implementation of standardised treatment protocols and procedural guidelines could enhance therapeutic outcomes and improve the accessibility of SRS for a broader range of patients.