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Vol 9, No 1 (2013)
Prace poglądowe
Published online: 2013-05-13
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Intestinal microbiota and its potential relationship with obesity

Wojciech Marlicz, Lucyna Ostrowska, Igor Łoniewski
Endokrynol. Otył. Zab. Przem. Mat 2013;9(1):20-28.

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Vol 9, No 1 (2013)
Prace poglądowe
Published online: 2013-05-13

Abstract

The general notion is that obesity is the result of various metabolicprocesses including energy absorption, storage and consumption.Positive energy balance is a consequence of overconsumptionof energy in the form of liquid, solid and semi-solid food, whichis stored in genetically programmed place — fat tissue. There isa growing body of evidence that metabolic processes are stronglyinfluenced and governed by intestinal microbiota. According to ourobservations, even patients who strictly adhere to and follow lowcaloric diets have difficulties to reduce body weight. As recentlypostulated, the answer might be in the gut microbiota, which isfrequently disturbed in obese persons. In this review, we presentrecent advances on the role of intestinal microbiota in the pathogenesisof obesity.We discuss current prophylactic and treatment modalities based onmicrobiota modulation with probiotics and prebiotics in overweightand obese people.

Abstract

The general notion is that obesity is the result of various metabolicprocesses including energy absorption, storage and consumption.Positive energy balance is a consequence of overconsumptionof energy in the form of liquid, solid and semi-solid food, whichis stored in genetically programmed place — fat tissue. There isa growing body of evidence that metabolic processes are stronglyinfluenced and governed by intestinal microbiota. According to ourobservations, even patients who strictly adhere to and follow lowcaloric diets have difficulties to reduce body weight. As recentlypostulated, the answer might be in the gut microbiota, which isfrequently disturbed in obese persons. In this review, we presentrecent advances on the role of intestinal microbiota in the pathogenesisof obesity.We discuss current prophylactic and treatment modalities based onmicrobiota modulation with probiotics and prebiotics in overweightand obese people.
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Keywords

obesity, intestinal microbiota, treatment and prophylaxis, probiotics, prebiotics

About this article
Title

Intestinal microbiota and its potential relationship with obesity

Journal

Endocrinology, Obesity and Metabolic Disorders

Issue

Vol 9, No 1 (2013)

Pages

20-28

Published online

2013-05-13

Bibliographic record

Endokrynol. Otył. Zab. Przem. Mat 2013;9(1):20-28.

Keywords

obesity
intestinal microbiota
treatment and prophylaxis
probiotics
prebiotics

Authors

Wojciech Marlicz
Lucyna Ostrowska
Igor Łoniewski

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