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open access

Vol 1, No 2 (2005)
Prace poglądowe
Published online: 2005-06-23
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Gut hormones regulating satiety: the gut–brain axis

Joanna Dytfeld, Danuta Pupek-Musialik
Endokrynol. Otył. Zab. Przem. Mat 2005;1(2):24-30.

open access

Vol 1, No 2 (2005)
Prace poglądowe
Published online: 2005-06-23

Abstract

Obesity and associated complications represent significant public health problem. Many advances have been made in the understanding of the homeostatic system that regulates body weight. In particular, much attention is focused on feeding control by the gastrointestinal tract hormones. Most of them cause meal termination and hence are called satiety signals. This group comprises cholecystokinin, PYY, GLP-1. The single gut-derived hormone that increases appetite discovered to date is ghrelin. Currently there is no effective cure to the pandemic of obesity. Practical use of the knowledge about gut hormones may offer an effective antiobesity therapy.

Abstract

Obesity and associated complications represent significant public health problem. Many advances have been made in the understanding of the homeostatic system that regulates body weight. In particular, much attention is focused on feeding control by the gastrointestinal tract hormones. Most of them cause meal termination and hence are called satiety signals. This group comprises cholecystokinin, PYY, GLP-1. The single gut-derived hormone that increases appetite discovered to date is ghrelin. Currently there is no effective cure to the pandemic of obesity. Practical use of the knowledge about gut hormones may offer an effective antiobesity therapy.
Get Citation

Keywords

PYY; ghrelin; GLP-1; obesity; gut hormones

About this article
Title

Gut hormones regulating satiety: the gut–brain axis

Journal

Endocrinology, Obesity and Metabolic Disorders

Issue

Vol 1, No 2 (2005)

Pages

24-30

Published online

2005-06-23

Page views

2868

Article views/downloads

17574

Bibliographic record

Endokrynol. Otył. Zab. Przem. Mat 2005;1(2):24-30.

Keywords

PYY
ghrelin
GLP-1
obesity
gut hormones

Authors

Joanna Dytfeld
Danuta Pupek-Musialik

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