Metabolic syndrome - controversies between academic debate and real world medical practice
Jan Tatoń, Małgorzata Bernas
Endokrynol. Otył. Zab. Przem. Mat 2008;4(1):13-26.
open access
Vol 4, No 1 (2008)
Prace poglądowe
Published online: 2008-02-07
Abstract
The expression „metabolic syndrome” points to the coexistence of
selected, mainly metabolic factors, forming the increased global risk of
atherosclerosis and of its complications. However the delineation of
such cluster of metabolic, atherogenic risk continue to be under discussion
resulting in many not always well evidenced definitions. They
are related to selected on different levels of evidence criteria, which
are not equivalent. Primary etiological mechanisms of the metabolic
syndrome are not known. This fact impairs all actual definition. It is
also the cause at many diagnostic, preventive and therapeutic difficulties
in clinical practice. The number of the risk factors of atherosclerosis
and of its complications is almost always greater than the
frames of definitions; the risk factors are also quantitatively different.
Therefore their delineation with the more dynamic concept emphasises
of “angiometabolic” risk could be more practical. It the
need for individualization, which could be more useful than the
academic discussion about the definitions.
It follows that such approach should be based on more individual
diagnostic plans. The proposal of such plan is presented.
Abstract
The expression „metabolic syndrome” points to the coexistence of
selected, mainly metabolic factors, forming the increased global risk of
atherosclerosis and of its complications. However the delineation of
such cluster of metabolic, atherogenic risk continue to be under discussion
resulting in many not always well evidenced definitions. They
are related to selected on different levels of evidence criteria, which
are not equivalent. Primary etiological mechanisms of the metabolic
syndrome are not known. This fact impairs all actual definition. It is
also the cause at many diagnostic, preventive and therapeutic difficulties
in clinical practice. The number of the risk factors of atherosclerosis
and of its complications is almost always greater than the
frames of definitions; the risk factors are also quantitatively different.
Therefore their delineation with the more dynamic concept emphasises
of “angiometabolic” risk could be more practical. It the
need for individualization, which could be more useful than the
academic discussion about the definitions.
It follows that such approach should be based on more individual
diagnostic plans. The proposal of such plan is presented.