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The impact of obesity on bone health: an overview
Affiliations- Serviço de Endocrinologia, Diabetes e Metabolismo, Centro Hospitalar e Universitário de S. João, Portugal
- Faculdade de Medicina da Universidade do Porto, Portugal
- Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Portugal
- Departamento de Biomedicina, Unidade de Bioquímica, Faculdade de Medicina da Universidade do Porto, Portugal
open access
Abstract
Obesity is a major health problem that has multisystemic consequences. One of the addressed topics in the current investigation regards the influence of obesity on bone metabolism. Despite of the broadly accepted notion that obesity is associated with a positive effect on bone health, recent evidence has challenged this idea by suggesting an increased risk of fracture in specific sites.
Therefore, this review intends to review succinctly the intricate connections between obesity and bone metabolism by addressing the roles of the mechanical, inflammatory, and hormonal factors, among others. It will also focus on the overall impact on bone mineral density and bone fracture occurrence.
Abstract
Obesity is a major health problem that has multisystemic consequences. One of the addressed topics in the current investigation regards the influence of obesity on bone metabolism. Despite of the broadly accepted notion that obesity is associated with a positive effect on bone health, recent evidence has challenged this idea by suggesting an increased risk of fracture in specific sites.
Therefore, this review intends to review succinctly the intricate connections between obesity and bone metabolism by addressing the roles of the mechanical, inflammatory, and hormonal factors, among others. It will also focus on the overall impact on bone mineral density and bone fracture occurrence.
Keywords
obesity; bone metabolism; bone mineral density; fractures
About this articleTitle
The impact of obesity on bone health: an overview
Journal
Issue
Article type
Review paper
Pages
954-958
Published online
2022-11-10
Page views
3796
Article views/downloads
669
DOI
Pubmed
Bibliographic record
Endokrynol Pol 2022;73(6):954-958.
Keywords
obesity
bone metabolism
bone mineral density
fractures
Authors
Fernando Miguel Mendonça
Raquel Soares
Davide Carvalho
Paula Freitas
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