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Van Wyk-Grumbach syndrome: a rare presentation of a common endocrine disorder
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Affiliations- Department of Endocrinology and Metabolism, IPGME and R/SSKM Hospital, Kolkata, India
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Abstract
Not required for Clinical Vignette.
Abstract
Not required for Clinical Vignette.
Keywords
Van Wyk and Grumbach; hypothyroidism; puberty; multicystic enlarged ovaries; pituitary; L-thyroxine
About this articleTitle
Van Wyk-Grumbach syndrome: a rare presentation of a common endocrine disorder
Journal
Issue
Article type
Clinical vignette
Pages
784-785
Published online
2022-06-29
Page views
4159
Article views/downloads
516
DOI
Pubmed
Bibliographic record
Endokrynol Pol 2022;73(4):784-785.
Keywords
Van Wyk and Grumbach
hypothyroidism
puberty
multicystic enlarged ovaries
pituitary
L-thyroxine
Authors
Pankaj Singhania
Rana Bhattarcharjee
Subhankar Chowdhury
References (7)- Wyk J, Grumbach M. Syndrome of precocious menstruation and galactorrhea in juvenile hypothyroidism: an example of hormonal overlap in pituitary feedback. Journal Pediatr. 1960; 57(3): 416–435.
- Wormsbecker A, Clarson C. Acquired primary hypothyroidism: vaginal bleeding in a quiet child. CMAJ. 2010; 182(6): 588–590.
- Baranowski E, Högler W. An unusual presentation of acquired hypothyroidism: the Van Wyk-Grumbach syndrome. Eur J Endocrinol. 2012; 166(3): 537–542.
- Chattopadhyay A, Kumar V, Marulaiah M. Polycystic ovaries, precocious puberty and acquired hypothyroidism: the Van Wyk and Grumbach syndrome. J Pediatr Surg. 2003; 38(9): 1390–1392.
- Indumathi CK, Bantwal G, Patil M. Primary hypothyroidism with precocious puberty and bilateral cystic ovaries. Indian J Pediatr. 2007; 74(8): 781–783.
- Advis JP, Richards JS, Ojeda SR. Hyperprolactinemia-induced precocious puberty: studies on the mechanism(s) by which prolactin enhances ovarian progesterone responsiveness to gonadotropins in prepubertal rats. Endocrinology. 1981; 108(4): 1333–1342.
- Durbin KL, Diaz-Montes T, Loveless MB. Van wyk and grumbach syndrome: an unusual case and review of the literature. J Pediatr Adolesc Gynecol. 2011; 24(4): e93–e96.
