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Primary hyperparathyroidism
Affiliations- Department of General and Endocrine Surgery, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Katowice, Poland
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Abstract
Primary hyperparathyroidism is an endocrine disorder that results in overproduction of parathyroid hormone by overactivated parathyroid gland leading to a significant rise in blood serum calcium. It results in hypercalcaemia, which has a significant impact mainly on the kidneys and bones and results in a variety of signs and symptoms. Primary hyperparathyroidism should be treated because, if left without any therapy, it can lead even to death. Surgery is considered as the best and only successful therapy, with very low risk of recurrence and relatively low complication rate. The aim of this review is to present clinical basis, aetiology, diagnostic possibilities, and treatment opportunities.
Abstract
Primary hyperparathyroidism is an endocrine disorder that results in overproduction of parathyroid hormone by overactivated parathyroid gland leading to a significant rise in blood serum calcium. It results in hypercalcaemia, which has a significant impact mainly on the kidneys and bones and results in a variety of signs and symptoms. Primary hyperparathyroidism should be treated because, if left without any therapy, it can lead even to death. Surgery is considered as the best and only successful therapy, with very low risk of recurrence and relatively low complication rate. The aim of this review is to present clinical basis, aetiology, diagnostic possibilities, and treatment opportunities.
Keywords
primary parathyroidism; hypercalcaemia; parathyroidectomy; parathormone
About this articleTitle
Primary hyperparathyroidism
Journal
Issue
Article type
Review paper
Pages
260-270
Published online
2020-06-30
Page views
4990
Article views/downloads
3907
DOI
Pubmed
Bibliographic record
Endokrynol Pol 2020;71(3):260-270.
Keywords
primary parathyroidism
hypercalcaemia
parathyroidectomy
parathormone
Authors
Grzegorz J. Kowalski
Grzegorz Buła
Dominika Żądło
Agata Gawrychowska
Jacek Gawrychowski
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