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Colorectal neuroendocrine neoplasms — management guidelines (recommended by the Polish Network of Neuroendocrine Tumours)
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Abstract
Neuroendocrine neoplasms of the large intestine account for 20% of all neuroendocrine neoplasms (NENs) and are most commonly found in the rectum. The rate of detection of colorectal NENs is increasing, and this tendency will continue due to the widespread use of colonoscopy as a screening tool and the removal of all diagnosed lesions. This paper provides updated guidelines for the management of patients with colorectal NENs. Recent data on epidemiology, clinical characteristics, biochemical, and pathomorphological diagnosis as well as useful imaging techniques are presented. We look in detail at novel methods of treatment including endoscopic and surgical management, pharmacological and radioisotope therapy. We summarise monitoring of the treatment. (Endokrynol Pol 2013; 64 (6): 494–504)
Abstract
Neuroendocrine neoplasms of the large intestine account for 20% of all neuroendocrine neoplasms (NENs) and are most commonly found in the rectum. The rate of detection of colorectal NENs is increasing, and this tendency will continue due to the widespread use of colonoscopy as a screening tool and the removal of all diagnosed lesions. This paper provides updated guidelines for the management of patients with colorectal NENs. Recent data on epidemiology, clinical characteristics, biochemical, and pathomorphological diagnosis as well as useful imaging techniques are presented. We look in detail at novel methods of treatment including endoscopic and surgical management, pharmacological and radioisotope therapy. We summarise monitoring of the treatment. (Endokrynol Pol 2013; 64 (6): 494–504)
Keywords
colorectal neuroendocrine neoplasms; epidemiology; diagnosis; treatment; follow-up
About this articleTitle
Colorectal neuroendocrine neoplasms — management guidelines (recommended by the Polish Network of Neuroendocrine Tumours)
Journal
Issue
Article type
Review paper
Pages
494-504
Published online
2013-12-31
Page views
3910
Article views/downloads
4446
DOI
10.5603/EP.2013.0032
Bibliographic record
Endokrynol Pol 2013;64(6):494-504.
Keywords
colorectal neuroendocrine neoplasms
epidemiology
diagnosis
treatment
follow-up
Authors
Teresa Starzyńska
Andrzej Deptała
Leszek Królicki
Jolanta Kunikowska
Magdalena Londzin-Olesik
Anna Nasierowska-Guttmejer
Marek Ruchała
Janusz Strzelczyk
Andrzej Szawłowski
Wojciech Zgliczyński
Beata Kos-Kudła
Other participants of the Consensus Conference (affiliations at the end of the paper):
Elżbieta Andrysiak-Mamos
Tomasz Bednarczuk
Jolanta Blicharz-Dorniak
Marek Bolanowski
Andrzej Cichocki
Jarosław B. Ćwikła
Wanda Foltyn
Daria Handkiewicz-Junak
Marek Hartleb
Alicja Hubalewska-Dydejczyk
Michał Jarząb
Arkadiusz Jeziorski
Dariusz Kajdaniuk
Grzegorz Kamiński
Aldona Kowalska
Robert Król
Katarzyna Kuśnierz
Paweł Lampe
Dariusz Lange
Anna Lewczuk
Magdalena Londzin-Olesik
Przemysław Majewski
Bogdan Marek
Gabriela Mełeń-Mucha
Andrzej Nowak
Ewa Nowakowska-Duława
Waldemar Patkowski
Joanna Pilch-Kowalczyk
Violetta Rosiek
Sławomir Rudzki
Philippe Ruszniewski
Grażyna Rydzewska
Anna Sowa-Staszczak
Katarzyna Steinhof-Radwańska
Wojciech Zajęcki
Piotr Zdunowski
Anna Zemczak
