open access

Vol 75, No 2 (2024)
Review paper
Submitted: 2024-02-23
Accepted: 2024-04-01
Published online: 2024-04-22
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Glycaemic control among adults with type 2 diabetes mellitus in the Gulf Cooperation Council countries: an updated review

Ahmad Ali Alrasheedi1
·
Pubmed: 38646983
·
Endokrynol Pol 2024;75(2):159-169.
Affiliations
  1. Department of Family and Community Medicine, College of Medicine, Qassim University, Saudi Arabia

open access

Vol 75, No 2 (2024)
Review Article
Submitted: 2024-02-23
Accepted: 2024-04-01
Published online: 2024-04-22

Abstract

Type 2 diabetes mellitus (T2DM) has become a major public health concern, causing significant disability and death worldwide. Fuelled by a modern sedentary lifestyle and poor dietary practices, T2DM affects at least 10.5% of the world’s population. This paper seeks to review the progress made by the Gulf Cooperation Council (GCC) countries (Bahrain, Kuwait, Oman, Qatar, Saudi Arabia, and the United Arab Emirates) in addressing T2DM, focusing on glycaemic control proportions and comparing it with the 2015 review. The results indicate no significant improvement in glycaemic control proportions since the last review, with only 9.2% to 56.9% of patients having good control (glycosylated haemoglobin < 7%). However, there are no significant differences in glycaemic control between the GCC countries and other places worldwide despite being considered hotbeds of T2DM. Many factors contribute to poor glycaemic control. Specifically, evidence shows that being overweight or obese is the most common modifiable risk factor for T2DM incidence and poor glycaemic control.

The GCC countries have higher rates of obesity. Additionally, poor glycaemic control is mainly related to a lack of adherence to insulin and medication use. Poor diet, rich in calories and low in fruits and vegetables, and a sedentary lifestyle also significantly contribute to poor glycaemic control and obesity. Therefore, to reduce the incidence of disease and improve glycaemic control in diabetic patients, educational programs promoting lifestyle changes should be implemented. Ongoing research is also necessary to assess the trend of glycaemic control and its risk factors in our region.

Abstract

Type 2 diabetes mellitus (T2DM) has become a major public health concern, causing significant disability and death worldwide. Fuelled by a modern sedentary lifestyle and poor dietary practices, T2DM affects at least 10.5% of the world’s population. This paper seeks to review the progress made by the Gulf Cooperation Council (GCC) countries (Bahrain, Kuwait, Oman, Qatar, Saudi Arabia, and the United Arab Emirates) in addressing T2DM, focusing on glycaemic control proportions and comparing it with the 2015 review. The results indicate no significant improvement in glycaemic control proportions since the last review, with only 9.2% to 56.9% of patients having good control (glycosylated haemoglobin < 7%). However, there are no significant differences in glycaemic control between the GCC countries and other places worldwide despite being considered hotbeds of T2DM. Many factors contribute to poor glycaemic control. Specifically, evidence shows that being overweight or obese is the most common modifiable risk factor for T2DM incidence and poor glycaemic control.

The GCC countries have higher rates of obesity. Additionally, poor glycaemic control is mainly related to a lack of adherence to insulin and medication use. Poor diet, rich in calories and low in fruits and vegetables, and a sedentary lifestyle also significantly contribute to poor glycaemic control and obesity. Therefore, to reduce the incidence of disease and improve glycaemic control in diabetic patients, educational programs promoting lifestyle changes should be implemented. Ongoing research is also necessary to assess the trend of glycaemic control and its risk factors in our region.

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Keywords

Arab; HbA1c; obesity; GCC; Middle East; Saudi Arabia

About this article
Title

Glycaemic control among adults with type 2 diabetes mellitus in the Gulf Cooperation Council countries: an updated review

Journal

Endokrynologia Polska

Issue

Vol 75, No 2 (2024)

Article type

Review paper

Pages

159-169

Published online

2024-04-22

Page views

120

Article views/downloads

53

DOI

10.5603/ep.99519

Pubmed

38646983

Bibliographic record

Endokrynol Pol 2024;75(2):159-169.

Keywords

Arab
HbA1c
obesity
GCC
Middle East
Saudi Arabia

Authors

Ahmad Ali Alrasheedi

References (86)
  1. Galicia-Garcia U, Benito-Vicente A, Jebari S, et al. Pathophysiology of Type 2 Diabetes Mellitus. Int J Mol Sci. 2020; 21(17).
  2. International Diabetes Federation: IDF Diabetes Atlas 10th edition 2021. https://diabetesatlas.org/atlas/tenth-edition/ (05.01.2024).
  3. American Diabetes Association Professional Practice Committee. 6. Glycemic Targets: Standards of Medical Care in Diabetes-2022. Diabetes Care. 2022; 45(Suppl 1): S83–S96.
  4. Davies MJ, D'Alessio DA, Fradkin J, et al. Management of Hyperglycemia in Type 2 Diabetes, 2018. A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetes Care. 2018; 41(12): 2669–2701.
  5. Bin Rakhis SA, AlDuwayhis NM, Aleid N, et al. Glycemic Control for Type 2 Diabetes Mellitus Patients: A Systematic Review. Cureus. 2022; 14(6): e26180.
  6. Wikipedia Gulf Cooperation Council. https://en.wikipedia.org/wiki/Gulf_Cooperation_Council (5.01.2024).
  7. Batniji R, Khatib L, Cammett M, et al. Governance and health in the Arab world. Lancet. 2014; 383(9914): 343–355.
  8. Al-Rasheedi A. Glycemic Control among Patients with Type 2 Diabetes Mellitus in Countries of Arabic Gulf. Int J Health Sci (Qassim). 2015; 9(3): 339–344.
  9. Alramadan MJ, Afroz A, Hussain SM, et al. Patient-Related Determinants of Glycaemic Control in People with Type 2 Diabetes in the Gulf Cooperation Council Countries: A Systematic Review. J Diabetes Res. 2018; 2018: 9389265.
  10. Al-Ma'aitah OH, Demant D, Jakimowicz S, et al. Glycaemic control and its associated factors in patients with type 2 diabetes in the Middle East and North Africa: An updated systematic review and meta-analysis. J Adv Nurs. 2022; 78(8): 2257–2276.
  11. GBD 2021 Diabetes Collaborators. Global, regional, and national burden of diabetes from 1990 to 2021, with projections of prevalence to 2050: a systematic analysis for the Global Burden of Disease Study 2021. Lancet. 2023; 402(10397): 203–234.
  12. El-Kebbi IM, Bidikian NH, Hneiny L, et al. Epidemiology of type 2 diabetes in the Middle East and North Africa: Challenges and call for action. World J Diabetes. 2021; 12(9): 1401–1425.
  13. International Diabetes Federation: IDF Diabetes Atlas 9th edition 2019. https://diabetesatlas.org/idfawp/resource-files/2019/07/IDF_diabetes_atlas_ninth_edition_en.pdf (10.01.2024).
  14. Aljulifi MZ. Prevalence and reasons of increased type 2 diabetes in Gulf Cooperation Council Countries. Saudi Med J. 2021; 42(5): 481–490.
  15. Alkandari A, Alarouj M, Elkum N, et al. Adult Diabetes and Prediabetes Prevalence in Kuwait: Data from the Cross-Sectional Kuwait Diabetes Epidemiology Program. J Clin Med. 2020; 9(11).
  16. Al Thani A, Fthenou E, Paparrodopoulos S, et al. Qatar Biobank Cohort Study: Study Design and First Results. Am J Epidemiol. 2019; 188(8): 1420–1433.
  17. Meo SA. Prevalence and future prediction of type 2 diabetes mellitus in the Kingdom of Saudi Arabia: A systematic review of published studies. J Pak Med Assoc. 2016; 66(6): 722–725.
  18. Al-Rubeaan K, Al-Manaa H, Khoja T, et al. The Saudi Abnormal Glucose Metabolism and Diabetes Impact Study (SAUDI-DM). Ann Saudi Med. 2014; 34(6): 465–475.
  19. Al Mansour MA. The Prevalence and Risk Factors of Type 2 Diabetes Mellitus (DMT2) in a Semi-Urban Saudi Population. Int J Environ Res Public Health. 2019; 17(1).
  20. Alawadi F, Abdelgadir E, Bashier A, et al. Glycemic Control in Patients with Diabetes across Primary and Tertiary Government Health Sectors in the Emirate of Dubai, United Arab Emirates: A Five-Year Pattern. Oman Med J. 2019; 34(1): 20–25.
  21. International Diabetes Federation: IDF Diabetes Atlas 8th edition 2017. https://diabetesatlas.org/atlas/eighth-edition/ (14.01.2024).
  22. Hamoudi R, Saheb Sharif-Askari N, Saheb Sharif-Askari F, et al. Prediabetes and diabetes prevalence and risk factors comparison between ethnic groups in the United Arab Emirates. Sci Rep. 2019; 9(1): 17437.
  23. Al-Mawali A, Al-Harrasi A, Jayapal SK, et al. Prevalence and risk factors of diabetes in a large community-based study in the Sultanate of Oman: STEPS survey 2017. BMC Endocr Disord. 2021; 21(1): 42.
  24. Salman RA, AlSayyad AS, Ludwig C. Type 2 diabetes and healthcare resource utilisation in the Kingdom of Bahrain. BMC Health Serv Res. 2019; 19(1): 939.
  25. Abubaker S, Albasseet A, El-Abd KA, et al. Association Between Vitamin D Levels and Glycemic Control Among Adult Diabetic Patients in Riyadh, Saudi Arabia. Cureus. 2022; 14(6): e25919.
  26. Alqahtani RM, Alsulami EF. The Association Between Glycated Hemoglobin (HbA1c) Level and Vitamin D Level in Diabetes Mellitus Patients: A Cross-Sectional Study. Cureus. 2023; 15(10): e47166.
  27. Ewid M, Algoblan AS, Elzaki EM, et al. Factors associated with glycemic control and diabetes complications in a group of Saudi patients with type 2 diabetes. Medicine (Baltimore). 2023; 102(38): e35212.
  28. Elfaki FA, Chandika RM, Kahlani SH, et al. Dietary patterns and their associations with glycemic control among type 2 diabetic patients in Jazan, Saudi Arabia: A cross-sectional study. Medicine (Baltimore). 2023; 102(28): e34296.
  29. Luhidan L. Rate of Glycemic Control and Prevalence of Associated Complications in Riyadh, Saudi Arabia 5 years Retrospective Chart Review of Adults in a tertiary care hospital and Primary Healthcare Clinics Among Adults with Type 2 Diabetes Mellitus Over 5 Years Period in Riyadh, Saudi Arabia. J Med Sci Clin Res. 2022; 10(02).
  30. Shaqra S, Bashawri H, Bahadur R, et al. Assessment of diabetes mellitus related knowledge and its association with glycemic control level among adult diabetic patients attending ministry of health primary health care centers in Makkah al Mukarramah, Saudi Arabia. Int J Health Sci. 2022; 6: 48452–48482.
  31. Alfadhli E, Sobhy G, Masoud R, et al. The Status of Metabolic Control in Patients With Diabetes Attending Primary Care Clinics in Madinah, Saudi Arabia. PREPRINT. (Version 1).
  32. Almalki Z, Ahmed N, Alahmari A, et al. Identifying the Risk Factors and the Prevalence of Poor Glycemic Control among Diabetic Outpatients in a Rural Region in Saudi Arabia. J Pharm Res Int. 2021: 15–23.
  33. Abouammoh NA, Alshamrani MA. Knowledge about Diabetes and Glycemic Control among Diabetic Patients in Saudi Arabia. J Diabetes Res. 2020; 2020: 1239735.
  34. Ghabban SJ, Althobaiti B, Farouk IM, et al. Diabetic Complications and Factors Affecting Glycemic Control Among Patients With Type II Diabetes Mellitus Attending the Chronic Illness Clinics at Tabuk, Saudi Arabia. Cureus. 2020; 12(11): e11683.
  35. Al Dossari KK, Ahmad G, Aljowair A, et al. Association of vitamin d with glycemic control in Saudi patients with type 2 diabetes: A retrospective chart review study in an emerging university hospital. J Clin Lab Anal. 2020; 34(2): e23048.
  36. Alzahrani SH, Baig M, Aashi MM, et al. Association between glycated hemoglobin (HbA1c) and the lipid profile in patients with type 2 diabetes mellitus at a tertiary care hospital: a retrospective study. Diabetes Metab Syndr Obes. 2019; 12: 1639–1644.
  37. Almetwazi M, Alwhaibi M, Balkhi B, et al. Factors associated with glycemic control in type 2 diabetic patients in Saudi Arabia. Saudi Pharm J. 2019; 27(3): 384–388.
  38. AlHamwy R, Hafiz M, Abuzied Y. Glycemic and Cardiovascular Risk Control among Patients with Type 2 Diabetes: A Saudi Tertiary Care Hospital Experience. Glob J Qual Safety Healthcare. 2019; 2(4): 89–97.
  39. Alzaheb RA, Altemani AH. The prevalence and determinants of poor glycemic control among adults with type 2 diabetes mellitus in Saudi Arabia. Diabetes Metab Syndr Obes. 2018; 11: 15–21.
  40. Alramadan MJ, Magliano DJ, Almigbal TH, et al. Glycaemic control for people with type 2 diabetes in Saudi Arabia - an urgent need for a review of management plan. BMC Endocr Disord. 2018; 18(1): 62.
  41. Bakhsh E, Qutub S. Levels and Barriers of Glycemic Control and Self-management Among Diabetic Patients in Primary Health Care in Jeddah: A Cross-sectional Study. Int J Adv Res. 2017; 5(12): 1721–1733.
  42. Al-Rasheedi AA. Glycemic Control among Patients with Type 2 Diabetes Mellitus Attending the Medical Clinics of Qassim University : Where Are We from the Targets ? Aljouf Univ Med J. 2017; 4(1): 31–38.
  43. Alsulaiman TA, Al-Ajmi HA, Al-Qahtani SM, et al. Control of type 2 diabetes in King Abdulaziz Housing City (Iskan) population, Saudi Arabia. J Family Community Med. 2016; 23(1): 1–5.
  44. Dabous RM, Younes ZH, Athamnah SB, et al. The effect of frequent diabetes self-management education on glucose control in patients with diabetes at the Dubai Diabetes Center in Dubai, United Arab Emirates. J Diab Endocrine Pract. 2022; 02(01): 8–12.
  45. Lee SM, Song I, Suh D, et al. Treatment Costs and Factors Associated with Glycemic Control among Patients with Diabetes in the United Arab Emirates. J Obes Metab Syndr. 2018; 27(4): 238–247.
  46. Tayyem R, Hamdan A, Alhmmadi K, et al. Association of Glycemic Control With Different Diets Followed by Patients With Type 2 Diabetes: Findings From Qatar Biobank Data. Front Nutr. 2022; 9: 813880.
  47. Alaradi M, Ouagueni A, Khatib R, et al. Dietary patterns and glycaemic control among Qatari adults with type 2 diabetes. Public Health Nutr. 2021; 24(14): 4506–4513.
  48. Mohamed HA, Al-Kohji SM, El-Din Makhlouf MM. Factors Associated with Glycemic Control among Type 2 Diabetic Patients Attending Primary Health Care Centers in Qatar, a Cross-Sectional Study. J Comm Med Publ Health. 2020; 4(2).
  49. Saleh MN, Alwahedi Z. Quality of Life Predictors and Glycemic Control among Type 2 Diabetic Patients Attending Primary Health Care Centers in Qatar. Primary Health Care Open Access. 2016; 6(2).
  50. Alkandari A, Gujral UP, Bennakhi A, et al. HbA1c, blood pressure, and cholesterol control in adults with diabetes: A report card for Kuwait. J Diabetes Investig. 2022; 13(10): 1732–1739.
  51. Hussein SH, Albatineh AN, Almajran A, et al. Association of health literacy and other risk factors with glycemic control among patients with type 2 diabetes in Kuwait: A cross-sectional study. Prim Care Diabetes. 2021; 15(3): 571–577.
  52. Abdullah A, Alkandari A, Longenecker JC, et al. Glycemic control in Kuwaiti diabetes patients treated with glucose-lowering medication. Prim Care Diabetes. 2020; 14(4): 311–316.
  53. Qaddoumi M, Al-Khamis Y, Channanath A, et al. The Status of Metabolic Control in Patients With Type 2 Diabetes Attending Dasman Diabetes Institute, Kuwait. Front Endocrinol (Lausanne). 2019; 10: 412.
  54. Alawainati MA, Ayoob ZA, AlQari AA, et al. Prevalence and characteristics of obesity in patients with type-2 diabetes mellitus in primary care centers in Bahrain: A cross-sectional study. J Family Community Med. 2023; 30(2): 109–115.
  55. Al-Rumayhi D, Bastawrous M, Bastawrous D. Factors affecting glycemic control among patients with type 2 diabetes in Bahrain. Bahrain Med Bull. 2019; 41: 146–149.
  56. Al Mahrouqi AS, Mallinson RK, Oh KMi, et al. Patient-centred care, diabetes self-management and glycaemic control among Omani patients with type-2 diabetes. Int J Nurs Pract. 2023; 29(1): e13103.
  57. D'Souza MS, Karkada SN, Hanrahan NP, et al. Do Perceptions of Empowerment Affect Glycemic Control and Self-Care Among Adults with Type 2 Diabetes? Glob J Health Sci. 2015; 7(5): 80–90.
  58. Al-Rubaee FR, Al-Abri MH. Characteristics of Registered Diabetics in Dhank Province in the Sultanate of Oman. Oman Med J. 2016; 31(3): 205–210.
  59. Bin Rakhis SA, AlDuwayhis NM, Aleid N, et al. Glycemic Control for Type 2 Diabetes Mellitus Patients: A Systematic Review. Cureus. 2022; 14(6): e26180.
  60. Grant B, Sandelson M, Agyemang-Prempeh B, et al. Managing obesity in people with type 2 diabetes. Clin Med (Lond). 2021; 21(4): e327–e231.
  61. World Obesity: Global Obesity Observatory. Data Tables, Prevalence of adult overweight & obesity (%). https://data.worldobesity.org/tables/prevalence-of-adult-overweight-obesity-2/ (01.12.2023).
  62. Mamdouh H, Hussain HY, Ibrahim GM, et al. Prevalence and associated risk factors of overweight and obesity among adult population in Dubai: a population-based cross-sectional survey in Dubai, the United Arab Emirates. BMJ Open. 2023; 13(1): e062053.
  63. Al-Quwaidhi AJ, Pearce MS, Critchley JA, et al. Trends and future projections of the prevalence of adult obesity in Saudi Arabia, 1992-2022. East Mediterr Health J. 2014; 20(10): 589–595.
  64. Al-Thani M, Al-Thani A, Alyafei S, et al. The prevalence and characteristics of overweight and obesity among students in Qatar. Public Health. 2018; 160: 143–149.
  65. Global Nutrition Report, 2020. Country Nutrition Profiles: Qatar. https://globalnutritionreport.org/resources/nutrition-profiles/asia/western-asia/qatar/#:~:text=46.1%25%20of%20adult%20(aged%2018,and%2021.8%25%20of%20adult%20men (01.12.2023).
  66. Althumiri NA, Basyouni MH, AlMousa N, et al. Obesity in Saudi Arabia in 2020: Prevalence, Distribution, and Its Current Association with Various Health Conditions. Healthcare (Basel). 2021; 9(3).
  67. Alsulami S, Baig M, Ahmad T, et al. Obesity prevalence, physical activity, and dietary practices among adults in Saudi Arabia. Front Public Health. 2023; 11: 1124051.
  68. Jatoi NA, Al-Qassab RM, Al Salem FH, et al. Prevalence of Obesity and Cardiovascular Risk Factors Among Type 2 Diabetes Mellitus Patients in Al-Khobar, Saudi Arabia. Cureus. 2022; 14(10): e30539.
  69. Bawady N, Aldafrawy O, ElZobair E, et al. Prevalence of Overweight and Obesity in Type 2 Diabetic Patients Visiting PHC in the Dubai Health Authority. Dubai Diab Endocrinol J. 2021; 28(1): 20–24.
  70. Awad SF, Al-Mawali A, Al-Lawati JA, et al. Forecasting the type 2 diabetes mellitus epidemic and the role of key risk factors in Oman up to 2050: Mathematical modeling analyses. J Diabetes Investig. 2021; 12(7): 1162–1174.
  71. Hazazi A, Wilson A. Noncommunicable diseases and health system responses in Saudi Arabia: focus on policies and strategies. A qualitative study. Health Res Policy Syst. 2022; 20(1): 63.
  72. Balhareth A, Meertens R, Kremers S, et al. Overweight and obesity among adults in the Gulf States: A systematic literature review of correlates of weight, weight-related behaviours, and interventions. Obes Rev. 2019; 20(5): 763–793.
  73. Mroueh L, Ayoub D, El-Hajj M, et al. Evaluation of medication adherence among Lebanese diabetic patients. Pharm Pract (Granada). 2018; 16(4): 1291.
  74. Chetoui A, Kaoutar K, Elmoussaoui S, et al. Prevalence and determinants of poor glycaemic control: a cross-sectional study among Moroccan type 2 diabetes patients. Int Health. 2022; 14(4): 390–397.
  75. Rashad BH, Abdi BA, Naqid IA, et al. Risk factors associated with poor glycemic control in patients with type two Diabetes mellitus in Zakho city. J Contemp Med Sci. 2021; 7(3).
  76. Abd-Elraouf MD. Factors Affecting Glycemic Control in Type II Diabetic Patients. Egypt J Hosp Med. 2020; 81(2): 1457–1461.
  77. Mousavi S, Tannenbaum Greenberg D, Ndjaboué R, et al. Diabetes Action Canada Research Questions Prioritization Study. The Influence of Age, Sex, and Socioeconomic Status on Glycemic Control Among People With Type 1 and Type 2 Diabetes in Canada: Patient-Led Longitudinal Retrospective Cross-sectional Study With Multiple Time Points of Measurement. JMIR Diabetes. 2023; 8: e35682.
  78. Presley CA, Khodneva Y, Juarez LD, et al. Trends and Predictors of Glycemic Control Among Adults With Type 2 Diabetes Covered by Alabama Medicaid, 2011-2019. Prev Chronic Dis. 2023; 20: E81.
  79. Huo L, Deng W, Shaw JE, et al. Factors associated with glycemic control in type 1 diabetes patients in China: A cross-sectional study. J Diabetes Investig. 2020; 11(6): 1575–1582.
  80. Borgharkar SS, Das SS. Real-world evidence of glycemic control among patients with type 2 diabetes mellitus in India: the TIGHT study. BMJ Open Diabetes Res Care. 2019; 7(1): e000654.
  81. Ibrahim AO, Agboola SM, Elegbede OT, et al. Glycemic control and its association with sociodemographics, comorbid conditions, and medication adherence among patients with type 2 diabetes in southwestern Nigeria. J Int Med Res. 2021; 49(10): 3000605211044040.
  82. Shita NG, Iyasu AS. Glycemic control and its associated factors in type 2 diabetes patients at Felege Hiwot and Debre Markos Referral Hospitals. Sci Rep. 2022; 12(1): 9459.
  83. Yahaya JJ, Doya IF, Morgan ED, et al. Poor glycemic control and associated factors among patients with type 2 diabetes mellitus: a cross-sectional study. Sci Rep. 2023; 13(1): 9673.
  84. Bitew ZW, Alemu A, Jember DA, et al. Prevalence of Glycemic Control and Factors Associated With Poor Glycemic Control: A Systematic Review and Meta-analysis. Inquiry. 2023; 60: 469580231155716.
  85. Al-Thani M, Al-Thani AA, Al-Mahdi N, et al. An Overview of Food Patterns and Diet Quality in Qatar: Findings from the National Household Income Expenditure Survey. Cureus. 2017; 9(5): e1249.
  86. Asfaw MS, Dagne WK. Physical activity can improve diabetes patients' glucose control; A systematic review and meta-analysis. Heliyon. 2022; 8(12): e12267.

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