Vol 71, No 3 (2020)
Review paper
Published online: 2020-06-30

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Primary hyperparathyroidism

Grzegorz J. Kowalski1, Grzegorz Buła1, Dominika Żądło1, Agata Gawrychowska1, Jacek Gawrychowski1
Pubmed: 32797471
Endokrynol Pol 2020;71(3):260-270.


Primary hyperparathyroidism is an endocrine disorder that results in overproduction of parathyroid hormone by overactivated parathyroid gland leading to a significant rise in blood serum calcium. It results in hypercalcaemia, which has a significant impact mainly on the kidneys and bones and results in a variety of signs and symptoms. Primary hyperparathyroidism should be treated because, if left without any therapy, it can lead even to death. Surgery is considered as the best and only successful therapy, with very low risk of recurrence and relatively low complication rate. The aim of this review is to present clinical basis, aetiology, diagnostic possibilities, and treatment opportunities.

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