open access

Vol 66, No 4 (2015)
Original papers
Published online: 2015-08-31
Submitted: 2014-10-02
Accepted: 2015-01-14
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Ultrasound-guided thyroid nodule fine-needle biopsies — comparison of sample adequacy with different sampling techniques, different needle sizes, and with/without onsite cytological analysis

Mahinur Cerit, Cem Yücel, Pınar Uyar Göçün, Aylar Poyraz, Ethem Turgay Cerit, Ferit Taneri
DOI: 10.5603/EP.2015.0037
·
Endokrynologia Polska 2015;66(4):295-300.

open access

Vol 66, No 4 (2015)
Original papers
Published online: 2015-08-31
Submitted: 2014-10-02
Accepted: 2015-01-14

Abstract

Introduction: The aim of this study was to compare the diagnostic adequacy of thyroid samples obtained by aspiration or capillary biopsy techniques, with 22 or 27 gauge needles, and with or without onsite cytological analysis (OCA).

Material and methods: Four hundred patients with thyroid nodules underwent ultrasound (US)-guided fine-needle biopsies. Patients were divided into eight groups according to needle size (22 vs. 27 gauge), biopsy technique (aspiration vs. capillary), and whether or not OCA was performed. Sample adequacy rates were calculated for each group and subgroups and compared using chi-square tests.

Results: When all nodes were evaluated (n = 400), the adequacy rate was significantly greater with the capillary than with the aspiration technique (97% vs. 91.5%, p = 0.032) and when OCA was than was not performed (97% vs. 91.5%, p = 0.032). When only solid nodules were evaluated (n = 205) the adequacy rate was also significantly greater with the capillary than with the aspiration technique (98.9% vs. 89.7%, p = 0.008) and when OCA was than was not performed (97.9% vs. 89.6%, p = 0.014). In contrast, the adequacy rate was similar for 22 and 27 gauge needles (94.2% vs. 93.1%, p = 0.733).

Conclusions: Optimal results were obtained with the capillary technique and OCA. The capillary technique and OCA should be the preferred approach in thyroid nodule biopsy, optimising adequacy rates and patient comfort. (Endokrynol Pol 2015; 66 (4): 295–300)

Abstract

Introduction: The aim of this study was to compare the diagnostic adequacy of thyroid samples obtained by aspiration or capillary biopsy techniques, with 22 or 27 gauge needles, and with or without onsite cytological analysis (OCA).

Material and methods: Four hundred patients with thyroid nodules underwent ultrasound (US)-guided fine-needle biopsies. Patients were divided into eight groups according to needle size (22 vs. 27 gauge), biopsy technique (aspiration vs. capillary), and whether or not OCA was performed. Sample adequacy rates were calculated for each group and subgroups and compared using chi-square tests.

Results: When all nodes were evaluated (n = 400), the adequacy rate was significantly greater with the capillary than with the aspiration technique (97% vs. 91.5%, p = 0.032) and when OCA was than was not performed (97% vs. 91.5%, p = 0.032). When only solid nodules were evaluated (n = 205) the adequacy rate was also significantly greater with the capillary than with the aspiration technique (98.9% vs. 89.7%, p = 0.008) and when OCA was than was not performed (97.9% vs. 89.6%, p = 0.014). In contrast, the adequacy rate was similar for 22 and 27 gauge needles (94.2% vs. 93.1%, p = 0.733).

Conclusions: Optimal results were obtained with the capillary technique and OCA. The capillary technique and OCA should be the preferred approach in thyroid nodule biopsy, optimising adequacy rates and patient comfort. (Endokrynol Pol 2015; 66 (4): 295–300)

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Keywords

thyroid nodule; biopsy technique; needle size

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About this article
Title

Ultrasound-guided thyroid nodule fine-needle biopsies — comparison of sample adequacy with different sampling techniques, different needle sizes, and with/without onsite cytological analysis

Journal

Endokrynologia Polska

Issue

Vol 66, No 4 (2015)

Pages

295-300

Published online

2015-08-31

DOI

10.5603/EP.2015.0037

Bibliographic record

Endokrynologia Polska 2015;66(4):295-300.

Keywords

thyroid nodule
biopsy technique
needle size

Authors

Mahinur Cerit
Cem Yücel
Pınar Uyar Göçün
Aylar Poyraz
Ethem Turgay Cerit
Ferit Taneri

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