Vol 64, No 6 (2013)
Review paper
Published online: 2013-12-31

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Colorectal neuroendocrine neoplasms — management guidelines (recommended by the Polish Network of Neuroendocrine Tumours)

Teresa Starzyńska, Andrzej Deptała, Leszek Królicki, Jolanta Kunikowska, Magdalena Londzin-Olesik, Anna Nasierowska-Guttmejer, Marek Ruchała, Janusz Strzelczyk, Andrzej Szawłowski, Wojciech Zgliczyński, Beata Kos-Kudła, Other participants of the Consensus Conference (affiliations at the end of the paper):, Elżbieta Andrysiak-Mamos, Tomasz Bednarczuk, Jolanta Blicharz-Dorniak, Marek Bolanowski, Andrzej Cichocki, Jarosław B. Ćwikła, Wanda Foltyn, Daria Handkiewicz-Junak, Marek Hartleb, Alicja Hubalewska-Dydejczyk, Michał Jarząb, Arkadiusz Jeziorski, Dariusz Kajdaniuk, Grzegorz Kamiński, Aldona Kowalska, Robert Król, Katarzyna Kuśnierz, Paweł Lampe, Dariusz Lange, Anna Lewczuk, Magdalena Londzin-Olesik, Przemysław Majewski, Bogdan Marek, Gabriela Mełeń-Mucha, Andrzej Nowak, Ewa Nowakowska-Duława, Waldemar Patkowski, Joanna Pilch-Kowalczyk, Violetta Rosiek, Sławomir Rudzki, Philippe Ruszniewski, Grażyna Rydzewska, Anna Sowa-Staszczak, Katarzyna Steinhof-Radwańska, Wojciech Zajęcki, Piotr Zdunowski, Anna Zemczak,
DOI: 10.5603/EP.2013.0032
Endokrynol Pol 2013;64(6):494-504.

Abstract

Neuroendocrine neoplasms of the large intestine account for 20% of all neuroendocrine neoplasms (NENs) and are most commonly found in the rectum. The rate of detection of colorectal NENs is increasing, and this tendency will continue due to the widespread use of colonoscopy as a screening tool and the removal of all diagnosed lesions. This paper provides updated guidelines for the management of patients with colorectal NENs. Recent data on epidemiology, clinical characteristics, biochemical, and pathomorphological diagnosis as well as useful imaging techniques are presented. We look in detail at novel methods of treatment including endoscopic and surgical management, pharmacological and radioisotope therapy. We summarise monitoring of the treatment. (Endokrynol Pol 2013; 64 (6): 494–504)