Vol 64, No 1 (2013)
Case report
Published online: 2013-02-28
Spontaneous regression of non-functioning pituitary adenoma due to pituitary apoplexy following anticoagulation treatment — a case report and review of the literature
Endokrynol Pol 2013;64(1):54-58.
Abstract
Pituitary apoplexy (PA) is a rare, potentially life-threatening medical condition due to acute ischaemia or haemorrhage of the pituitary gland.
The main clinical features are: abrupt onset of severe headache, nausea, vomiting, deteriorating level of consciousness, visual impairment
and/or endocrine deficiency. Correct and prompt diagnosis is essential for effective therapy, but there are no randomised studies or strict
recommendations defining treatment modalities. We present the case of a 59 year-old woman with pituitary tumour apoplexy, presenting
with severe headache, vomiting and visual field deterioration. The patient was treated conservatively because of her refusal of surgery and
was followed-up for five years. In the course of treatment, recovery of the visual field defects, as well as right sixth cranial nerve paresis,
was observed. Repeated magnetic resonance imaging (MRI) revealed regression of the tumour without signs of its re-growth. We discuss
therapeutic modalities with particular emphasis on morbidity and review the literature relating to the management of pituitary tumour
apoplexy.
Keywords: pituitary apoplexyhypopituitarismdeep venous thrombosispituitary tumourtranssphenoidal surgery