Biochemical symptoms of hypothyreosis in the population of Warsaw region

Abstract

Doctors in Warsaw region claimed that the results of fT4 and TSH examinations originating from different laboratories are incomparable. Therefore the Gaussian Reference Ranges (GRR) of archival sets of data from 6 laboratories (together 18793 fT4 and 44851 TSH results) were calculated separately with JEG method. The upper and lover ranges were compared with data from 11 bibliographical sources. It was found that in the investigated population the both averaged ranges (high and low) of GRR of fT4 are statistical significant lover then the reference data. In the same time the averaged upper range of GRR of TSH was higher than the averaged data from the literature. Based on statistic analysis of these results it could be estimated that about 20% of the investigated population show evident and about 50% show moderate signs of hypothyreosis.