Place of thyroglobulin antibodies assay in laboratory diagnostic of autoimmune thyroid diseases

Ewa Jastrzębska-Bohaterewicz; Wanda Wojciechowska; Andrzej Gardas

Vol 56, No 1 (2005)

Original paper

Submitted: 2013-02-15

Published online: 2006-03-22

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Place of thyroglobulin antibodies assay in laboratory diagnostic of autoimmune thyroid diseases

Ewa Jastrzębska-Bohaterewicz, Wanda Wojciechowska, Andrzej Gardas

Endokrynol Pol 2005;56(1):30-34.

Vol 56, No 1 (2005)

Original Paper

Submitted: 2013-02-15

Published online: 2006-03-22

Abstract

Tyroglobulin and thyroid peroxidase antibodies have been estimated in patients with thyroid autoimmune diseases. In a group of 109 patients with Hashimoto’s thyroidities 85.53% and 78.89% were positive for Tyroglobulin antibodies and anti-TPO antibodies respectively. The anti-Tg antibodies has not been detected in 14.67% and anti-TPO in 21.1% patients. Both antibodies have not been detected in 1.83% of patients.
In a group of 79 patients with Graves’ disease 62.02 and 91.13% were positive for anti-Tg and anti-TPO antibodies respectively. The anti-Tg antibodies has not been detected in 37.97% and anti-TPO in 8.66% patients. Both antibodies have not been detected in one patients with exophtalmos (1.26%). Our results indicate that anti-tyroglobulin antibodies should be estimated only in patients suspected for thyroid autoimmune disease and negative for thyroid peroxidase antibodies.