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Vol 56, No 5 (2005)
Original paper
Submitted: 2013-02-15
Published online: 2006-05-28
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Clinical course and treatment of patients with differentiated

Agnieszka Czarniecka, Jan Włoch, Michał Jarząb, Jolanta Krajewska, Aleksandra Kukulska, Józef Roskosz, Zbigniew Puch, Aleksandra. Wróbel, Magdalena Wollak, Maria Turska, Zoran Stojcev, Bogusław Mąka
Endokrynol Pol 2005;56(5):758-765.

open access

Vol 56, No 5 (2005)
Original Paper
Submitted: 2013-02-15
Published online: 2006-05-28

Abstract

The aim of the study was to analyze the clinical course and therapy in patients with differentiated thyroid carcinoma (DTC) diagnosed in Poland within the year 1995. The group of 478 patients with thyroid cancer (57.7% of all thyroid cancer cases diagnosed this year in Poland) was analyzed. Patients were diagnosed or treated in Maria Skłodowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice Branch. Detailed analysis was performed in 352 patients with DTC who were treated by surgery. 292 patients (60%) received adjuvant radioiodine therapy. Hormonal (L-thyroxine) treatment was administered to all patients. In 37 patients (8.6%) local recurrence was observed. 10-year overall survival was 96.4% and disease-free survival was respectively 68%. The comparison of Polish data to analysis in German population published by Holtzer et al. (Cancer, 2000) was also performed in this study. We conclude that DTC therapy, currently recommended in our country, gives satisfactory results and that clinical outcome and therapeutic methods are similar both in Poland and Germany.

Abstract

The aim of the study was to analyze the clinical course and therapy in patients with differentiated thyroid carcinoma (DTC) diagnosed in Poland within the year 1995. The group of 478 patients with thyroid cancer (57.7% of all thyroid cancer cases diagnosed this year in Poland) was analyzed. Patients were diagnosed or treated in Maria Skłodowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice Branch. Detailed analysis was performed in 352 patients with DTC who were treated by surgery. 292 patients (60%) received adjuvant radioiodine therapy. Hormonal (L-thyroxine) treatment was administered to all patients. In 37 patients (8.6%) local recurrence was observed. 10-year overall survival was 96.4% and disease-free survival was respectively 68%. The comparison of Polish data to analysis in German population published by Holtzer et al. (Cancer, 2000) was also performed in this study. We conclude that DTC therapy, currently recommended in our country, gives satisfactory results and that clinical outcome and therapeutic methods are similar both in Poland and Germany.

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Keywords

differentiated thyroid cancer; combined therapy

About this article
Title

Clinical course and treatment of patients with differentiated

Journal

Endokrynologia Polska

Issue

Vol 56, No 5 (2005)

Article type

Original paper

Pages

758-765

Published online

2006-05-28

Page views

543

Article views/downloads

872

Bibliographic record

Endokrynol Pol 2005;56(5):758-765.

Keywords

differentiated thyroid cancer
combined therapy

Authors

Agnieszka Czarniecka
Jan Włoch
Michał Jarząb
Jolanta Krajewska
Aleksandra Kukulska
Józef Roskosz
Zbigniew Puch
Aleksandra. Wróbel
Magdalena Wollak
Maria Turska
Zoran Stojcev
Bogusław Mąka

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