The principles and the routes of progestagenes&#8217; administration in PCOS

Józef Krzysiek; Magdalena Krzyczkowska-Sendrakowska; Tomasz Milewicz

Vol 56, No 6 (2005)

Review paper

Submitted: 2013-02-15

Published online: 2006-06-26

View PDF (Polish)

Download PDF file

Get Citation

The principles and the routes of progestagenes’ administration in PCOS

Józef Krzysiek, Magdalena Krzyczkowska-Sendrakowska, Tomasz Milewicz

Endokrynol Pol 2005;56(6):1002-1007.

Vol 56, No 6 (2005)

Review Article

Submitted: 2013-02-15

Published online: 2006-06-26

Abstract

One of the chief findings in polycystic ovaries syndrome may be the defective luteal phase of the menstrual cycle. There is a growing list of publications indicating a defective progesterone production by granulosa cells of ovarian follicles. In consequence, women with polycystic ovaries often require both the luteal phase and early pregnancy supplementation. From different routes of progesterone administration during the menstrual cycle, as the most clinically reliable in the early pregnancy either intramuscular or intravaginal route has been recommended.