open access

Vol 56, No 6 (2005)
Review article
Published online: 2006-06-26
Submitted: 2013-02-15
Get Citation

Potential application of stem cells in urogynecology

Aneta Adamiak, Tomasz Rechberger
Endokrynologia Polska 2005;56(6):994-997.

open access

Vol 56, No 6 (2005)
Review article
Published online: 2006-06-26
Submitted: 2013-02-15

Abstract

Recent advances in stem cells therapy and tissue engineering techniques hold great promise for recovery of external urethral sphincter proper functioning and urinary incontinent patients treatment. Adult stem cells (ASCs) may be derived from striated muscles, fat tissue or as mesenchymal cells from bone marrow. These cells can differentiate in functionally normal smooth or striated muscle cells. ASCs injected to external urethral sphincter or bladder neck cause the increase in urethral closure pressure. Favourable findings of trials in animal models and in vitro encouraged to first trials in humans and hold a promising future for the treatment of urinary incontinence.

Abstract

Recent advances in stem cells therapy and tissue engineering techniques hold great promise for recovery of external urethral sphincter proper functioning and urinary incontinent patients treatment. Adult stem cells (ASCs) may be derived from striated muscles, fat tissue or as mesenchymal cells from bone marrow. These cells can differentiate in functionally normal smooth or striated muscle cells. ASCs injected to external urethral sphincter or bladder neck cause the increase in urethral closure pressure. Favourable findings of trials in animal models and in vitro encouraged to first trials in humans and hold a promising future for the treatment of urinary incontinence.
Get Citation

Keywords

stem cells; urinary incontinence

About this article
Title

Potential application of stem cells in urogynecology

Journal

Endokrynologia Polska

Issue

Vol 56, No 6 (2005)

Pages

994-997

Published online

2006-06-26

Bibliographic record

Endokrynologia Polska 2005;56(6):994-997.

Keywords

stem cells
urinary incontinence

Authors

Aneta Adamiak
Tomasz Rechberger

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