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Vol 56, No 6 (2005)
Case report
Submitted: 2013-02-15
Published online: 2006-06-26
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Gynecomasty as a first sign of adrenal carcinoma - case report

Izabella Czajka, Wojciech Zgliczyński, Anna Kasperlik-Załuska, Andrzej Cichocki
DOI: 10.5603/ep.25790
·
Endokrynol Pol 2005;56(6):940-944.

open access

Vol 56, No 6 (2005)
Case report
Submitted: 2013-02-15
Published online: 2006-06-26

Abstract

We present a case of 50 year-old man with feminizing adrenal carcinoma. He was admitted to the hospital because of weekness and one year history of gynecomastia and high blood presure. Examinations revealed a large left adrenal mass and increased levels of estradiol. Patient underwent adrenalecomy and followed by mitotan therapy as the result of histopathological examination was adrenocortical carcinoma. One year after operation patient stays free from the recurence of the disease and his estradiol, androstendion and DHEA levels are below the detection limits.
We report this case because feminizing adrenal carcinoma is a very rare but serious disease and gynecomastia that could be its manifestation is quite frequent symptom in men’s population and thus it could easily be missed. In every case of gynecomastia related to estradiol excess feminizing tumors of testis and adrenal gland should be ruled out.

Abstract

We present a case of 50 year-old man with feminizing adrenal carcinoma. He was admitted to the hospital because of weekness and one year history of gynecomastia and high blood presure. Examinations revealed a large left adrenal mass and increased levels of estradiol. Patient underwent adrenalecomy and followed by mitotan therapy as the result of histopathological examination was adrenocortical carcinoma. One year after operation patient stays free from the recurence of the disease and his estradiol, androstendion and DHEA levels are below the detection limits.
We report this case because feminizing adrenal carcinoma is a very rare but serious disease and gynecomastia that could be its manifestation is quite frequent symptom in men’s population and thus it could easily be missed. In every case of gynecomastia related to estradiol excess feminizing tumors of testis and adrenal gland should be ruled out.

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Keywords

gynekomastia; feminizing adrenal carcinoma; estradiol

About this article
Title

Gynecomasty as a first sign of adrenal carcinoma - case report

Journal

Endokrynologia Polska

Issue

Vol 56, No 6 (2005)

Article type

Case report

Pages

940-944

Published online

2006-06-26

Page views

727

Article views/downloads

4151

DOI

10.5603/ep.25790

Bibliographic record

Endokrynol Pol 2005;56(6):940-944.

Keywords

gynekomastia
feminizing adrenal carcinoma
estradiol

Authors

Izabella Czajka
Wojciech Zgliczyński
Anna Kasperlik-Załuska
Andrzej Cichocki

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