open access

Vol 56, No 6 (2005)
Original papers
Published online: 2006-06-26
Submitted: 2013-02-15
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The relationship between testosterone and dehydroepiandrosterone sulfate concentrations, insulin resistance and visceral obesity in elderly men

Michał Rabijewski, Jarosław Kozakowski, Wojciech Zgliczyński
Endokrynologia Polska 2005;56(6):897-903.

open access

Vol 56, No 6 (2005)
Original papers
Published online: 2006-06-26
Submitted: 2013-02-15

Abstract

Introduction. Sex hormones deficiency - hypotestosteronemia (20-30% of men) and dehydroepian-drosterone sulfate deficiency (60-70% of men) are often observed in elderly men. In these men also changes of body composition (visceral obesity, increasing of fat mass), and metabolic disturbances (hypercholesterolemia, hyperinsulinism and insulin resistance) are common disorders. Visceral obesity and insulin resistance may be either reasons or effects of testosterone deficiency. Probably also DHEA-S deficiency is the risk factor of visceral obesity and insulin resistance, but it is not clear, whether this possible influence is independent from testosterone deficiency.
Objectives. The aim of this study was to analyze the association between testosterone and DHEA deficiency and waist/hip ratio (WHR), levels of glucose and insulin resistance (HOMA and FG/FI) in elderly men as well as analysis, whether these sex hormones influent on measured parameters separately.
Material and methods. Together 85 men with age from 60 to 70 years men (mean 66,3±1,5 years; mean±SEM) was analyzed. Testosterone levels

Abstract

Introduction. Sex hormones deficiency - hypotestosteronemia (20-30% of men) and dehydroepian-drosterone sulfate deficiency (60-70% of men) are often observed in elderly men. In these men also changes of body composition (visceral obesity, increasing of fat mass), and metabolic disturbances (hypercholesterolemia, hyperinsulinism and insulin resistance) are common disorders. Visceral obesity and insulin resistance may be either reasons or effects of testosterone deficiency. Probably also DHEA-S deficiency is the risk factor of visceral obesity and insulin resistance, but it is not clear, whether this possible influence is independent from testosterone deficiency.
Objectives. The aim of this study was to analyze the association between testosterone and DHEA deficiency and waist/hip ratio (WHR), levels of glucose and insulin resistance (HOMA and FG/FI) in elderly men as well as analysis, whether these sex hormones influent on measured parameters separately.
Material and methods. Together 85 men with age from 60 to 70 years men (mean 66,3±1,5 years; mean±SEM) was analyzed. Testosterone levels
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Keywords

hypogonadism; DHEA-S; men; obesity; insulin resistance

About this article
Title

The relationship between testosterone and dehydroepiandrosterone sulfate concentrations, insulin resistance and visceral obesity in elderly men

Journal

Endokrynologia Polska

Issue

Vol 56, No 6 (2005)

Pages

897-903

Published online

2006-06-26

Bibliographic record

Endokrynologia Polska 2005;56(6):897-903.

Keywords

hypogonadism
DHEA-S
men
obesity
insulin resistance

Authors

Michał Rabijewski
Jarosław Kozakowski
Wojciech Zgliczyński

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