Multimedialna platforma wiedzy medycznej Internetowa Księgarnia Medyczna Kalendarium Konferencji
Endokrynologia Polska
MENU
Shortcuts Submit an article Author Guidelines Polish Society of Endocrinology Old electronic manuscript service

open access

Vol 57, No 2 (2006)
Review article
Published online: 2006-05-26
Submitted: 2013-02-15
View PDF (polish) Download PDF file
Get Citation

Current knowledge on aquaporin water channels: clinical implications

Małgorzata Jasiewicz, Janusz Myśliwiec
Endokrynologia Polska 2006;57(2):149-157.

open access

Vol 57, No 2 (2006)
Review article
Published online: 2006-05-26
Submitted: 2013-02-15

Abstract

The discovery of the aquaporin family of water channels has explained to a high degree the mechanism of water transport across cell membranes. The molecular structure of the first purified aquaporin shows its tetrameric organization with each subunit containing an individual aqueous pore selectively permeable for water but not for protons. At least 11 human aquaporins have been identified. Definition of sites of their expression enabled explanation of their physiological role as well as pathological importance in congenital cataract or nephrogenic diabetes insipidus.

Abstract

The discovery of the aquaporin family of water channels has explained to a high degree the mechanism of water transport across cell membranes. The molecular structure of the first purified aquaporin shows its tetrameric organization with each subunit containing an individual aqueous pore selectively permeable for water but not for protons. At least 11 human aquaporins have been identified. Definition of sites of their expression enabled explanation of their physiological role as well as pathological importance in congenital cataract or nephrogenic diabetes insipidus.

Full Text:

View PDF (polish) Download PDF file
Get Citation

Keywords

aquaporins; congenital cataract; diabetes insipidus

About this article
Title

Current knowledge on aquaporin water channels: clinical implications

Journal

Endokrynologia Polska

Issue

Vol 57, No 2 (2006)

Pages

149-157

Published online

2006-05-26

Bibliographic record

Endokrynologia Polska 2006;57(2):149-157.

Keywords

aquaporins
congenital cataract
diabetes insipidus

Authors

Małgorzata Jasiewicz
Janusz Myśliwiec

Important: This website uses cookies. More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

Via MedicaWydawcą serwisu jest  "Via Medica sp. z o.o." sp.k., ul. Świętokrzyska 73, 80–180 Gdańsk

tel.:+48 58 320 94 94, faks:+48 58 320 94 60, e-mail:  viamedica@viamedica.pl