Vol 57, No 3 (2006)
Case report
Published online: 2006-06-28
Family incidence of latent autoimmune diabetes in adults - case report
Endokrynol Pol 2006;57(3):254-257.
Abstract
We describe a 37 year-old woman case of latent autoimmune
diabetes in adults (LADA). She was presented with unfounded
weight loss. The diagnosis of diabetes mellitus was
established on twice plasma glucose measurements above
200 mg/dl. In other routine biochemical examinations we did
not observe dehydratation, electrolyte depletion, acidosis.
However plasma level of C peptide basal and after stimulation
with glucagon was reduced. Initially, the patient responded
well to sulphonylurea treatment. To test immunological
pathogenesis we examine autoimmune markers
of diabetes type 1. Autoimmune antibodies (GAD, IAA) were
found in patients and her parents, which were until now
diabetic type 2.
We report this case because incidence of latent autoimmune
diabetes in adults is underestimate and rarely diagnosed
in clinical practice.
Keywords: latent autoimmune diabetes in adults (LADA)GADAIAA
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