open access

Vol 57, No 3 (2006)
Case report
Published online: 2006-06-28
Submitted: 2013-02-15
Get Citation

Family incidence of latent autoimmune diabetes in adults - case report

Barbara Szepietowska, Małgorzata Szelachowska, Maria Górska
Endokrynologia Polska 2006;57(3):254-257.

open access

Vol 57, No 3 (2006)
Case report
Published online: 2006-06-28
Submitted: 2013-02-15

Abstract

We describe a 37 year-old woman case of latent autoimmune diabetes in adults (LADA). She was presented with unfounded weight loss. The diagnosis of diabetes mellitus was established on twice plasma glucose measurements above 200 mg/dl. In other routine biochemical examinations we did not observe dehydratation, electrolyte depletion, acidosis. However plasma level of C peptide basal and after stimulation with glucagon was reduced. Initially, the patient responded well to sulphonylurea treatment. To test immunological pathogenesis we examine autoimmune markers of diabetes type 1. Autoimmune antibodies (GAD, IAA) were found in patients and her parents, which were until now diabetic type 2. We report this case because incidence of latent autoimmune diabetes in adults is underestimate and rarely diagnosed in clinical practice.

Abstract

We describe a 37 year-old woman case of latent autoimmune diabetes in adults (LADA). She was presented with unfounded weight loss. The diagnosis of diabetes mellitus was established on twice plasma glucose measurements above 200 mg/dl. In other routine biochemical examinations we did not observe dehydratation, electrolyte depletion, acidosis. However plasma level of C peptide basal and after stimulation with glucagon was reduced. Initially, the patient responded well to sulphonylurea treatment. To test immunological pathogenesis we examine autoimmune markers of diabetes type 1. Autoimmune antibodies (GAD, IAA) were found in patients and her parents, which were until now diabetic type 2. We report this case because incidence of latent autoimmune diabetes in adults is underestimate and rarely diagnosed in clinical practice.
Get Citation

Keywords

latent autoimmune diabetes in adults (LADA); GADA; IAA

About this article
Title

Family incidence of latent autoimmune diabetes in adults - case report

Journal

Endokrynologia Polska

Issue

Vol 57, No 3 (2006)

Pages

254-257

Published online

2006-06-28

Bibliographic record

Endokrynologia Polska 2006;57(3):254-257.

Keywords

latent autoimmune diabetes in adults (LADA)
GADA
IAA

Authors

Barbara Szepietowska
Małgorzata Szelachowska
Maria Górska

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