open access

Vol 57, No 4 (2006)
Original papers
Published online: 2006-07-07
Submitted: 2013-02-15
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The impact of the extent and time of operation on the survival in patients with differentiated thyroid carcinoma (DTC)

Agnieszka Czarniecka, Michał Jarząb, Jolanta Krajewska, Aleksander Sacher, Stanisław Półtorak, Jan Włoch
Endokrynologia Polska 2006;57(4):347-355.

open access

Vol 57, No 4 (2006)
Original papers
Published online: 2006-07-07
Submitted: 2013-02-15

Abstract

Introduction: To analyze the impact of time and extent of operation on overall and disease-free survival in patients with differentiated thyroid carcinoma (DTC).
Material and methods T1M0. 10-year outcomes were analyzed by Kaplan-Meier survival curves and Cox proportional-hazard model.
Results T1M0 group the survival was better in patients who were treated by total thyroidectomy (94% and 68% respectively) than in patients treated by non-total thyroidectomy (78% and 47% respectively). In patients treated by completion of total thyroidectomy delayed more than 1 year post cancer diagnosis the incidence of carcinoma in postoperative pathological material was twice as high in comparison to the group in whom total thyroidectomy was performed within the first year of therapy (p = 0.000).
Conclusions: 1. In differentiated thyroid carcinoma the prognosis is related to the extent of operation only in patients staged more than T1M0. 1 cm of diameter) significantly increases the risk of progression of multifocal disease in thyroid remnants.

Abstract

Introduction: To analyze the impact of time and extent of operation on overall and disease-free survival in patients with differentiated thyroid carcinoma (DTC).
Material and methods T1M0. 10-year outcomes were analyzed by Kaplan-Meier survival curves and Cox proportional-hazard model.
Results T1M0 group the survival was better in patients who were treated by total thyroidectomy (94% and 68% respectively) than in patients treated by non-total thyroidectomy (78% and 47% respectively). In patients treated by completion of total thyroidectomy delayed more than 1 year post cancer diagnosis the incidence of carcinoma in postoperative pathological material was twice as high in comparison to the group in whom total thyroidectomy was performed within the first year of therapy (p = 0.000).
Conclusions: 1. In differentiated thyroid carcinoma the prognosis is related to the extent of operation only in patients staged more than T1M0. 1 cm of diameter) significantly increases the risk of progression of multifocal disease in thyroid remnants.
Get Citation

Keywords

differentiated thyroid carcinoma; extent and time of surgery; prognosis

About this article
Title

The impact of the extent and time of operation on the survival in patients with differentiated thyroid carcinoma (DTC)

Journal

Endokrynologia Polska

Issue

Vol 57, No 4 (2006)

Pages

347-355

Published online

2006-07-07

Bibliographic record

Endokrynologia Polska 2006;57(4):347-355.

Keywords

differentiated thyroid carcinoma
extent and time of surgery
prognosis

Authors

Agnieszka Czarniecka
Michał Jarząb
Jolanta Krajewska
Aleksander Sacher
Stanisław Półtorak
Jan Włoch

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