Angiogenic and anti-angiogenic factors in adrenal tumours

Jolanta Jurczyńska; Wojciech Zieleniewski; Henryk Stępień; Jan Komorowski

Vol 57, No 6 (2006)

Review paper

Submitted: 2013-02-15

Published online: 2006-11-29

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Angiogenic and anti-angiogenic factors in adrenal tumours

Jolanta Jurczyńska, Wojciech Zieleniewski, Henryk Stępień, Jan Komorowski

Endokrynol Pol 2006;57(6):633-640.

Vol 57, No 6 (2006)

Review Article

Submitted: 2013-02-15

Published online: 2006-11-29

Abstract

It appears that neoangiogenesis is an important factor in tumour invasion and the formation of metastases in several human cancers, and studies on pro-angiogenic and antiangiogenic factors are therefore of considerable interest to researchers. In this review we present pro-angiogenic and anti-angiogenic factors and other growth factors and their role in the formation of new blood vessels in adrenal tumours. Assessment of the angiogenic status of adrenal tumours and their vascular pattern may be useful for discriminating benign from malignant lesions and knowledge of their angiogenesis may be essential to the drawing up of promising treatment strategies for patients with malignant tumours.