open access

Vol 57, No 6 (2006)
Review article
Published online: 2006-11-29
Submitted: 2013-02-15
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The adiponectin role in pathogenesis of metabolic syndrome and cardiovascular disease

Agnieszka Kozłowska, Irina Kowalska
Endokrynologia Polska 2006;57(6):626-632.

open access

Vol 57, No 6 (2006)
Review article
Published online: 2006-11-29
Submitted: 2013-02-15

Abstract

The aim of this review is to present the up-to-date data about adiponectin and it’s role in pathogenesis of cardiovascular disease. Adiponectin is a hormone derived from adipose tissue which regulates energy metabolism, and plays an important role in the pathogenesis of insulin resistance. Serum levels of adiponectin are reduced in obesity, hypertension, metabolic syndrome and type 2 diabetes. Moreover, plasma adiponectin concentration is inversely associated with LDL-cholesterol, TG and is positively related to HDLcholesterol. Recent studies have indicated that adiponectin has antiinflammatory and antiatherogenic properties. Review of the data confirmed the hypothesis that adiponectin plays an important role in pathogenesis of cardiovascular disease.

Abstract

The aim of this review is to present the up-to-date data about adiponectin and it’s role in pathogenesis of cardiovascular disease. Adiponectin is a hormone derived from adipose tissue which regulates energy metabolism, and plays an important role in the pathogenesis of insulin resistance. Serum levels of adiponectin are reduced in obesity, hypertension, metabolic syndrome and type 2 diabetes. Moreover, plasma adiponectin concentration is inversely associated with LDL-cholesterol, TG and is positively related to HDLcholesterol. Recent studies have indicated that adiponectin has antiinflammatory and antiatherogenic properties. Review of the data confirmed the hypothesis that adiponectin plays an important role in pathogenesis of cardiovascular disease.
Get Citation

Keywords

adiponectin; metabolic syndrome; cardiovascular disease

About this article
Title

The adiponectin role in pathogenesis of metabolic syndrome and cardiovascular disease

Journal

Endokrynologia Polska

Issue

Vol 57, No 6 (2006)

Pages

626-632

Published online

2006-11-29

Bibliographic record

Endokrynologia Polska 2006;57(6):626-632.

Keywords

adiponectin
metabolic syndrome
cardiovascular disease

Authors

Agnieszka Kozłowska
Irina Kowalska

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