DOI: 10.5603/ep.25646
·
Endokrynol Pol 2007;58(2):153-163.
Vol 58, No 2 (2007)
Review Article
Submitted: 2013-02-15
Published online: 2007-03-13
Abstract
Ageing is doubtless complicated, lifelong process regarding many body systems, including endocrine system. Human hormonal system changes with age. Although these changes concern secretion of many hormones, they are not unidirectional, there are hormones secretion of which is diminished, whereas secretion of the others is augmented or not changed with age. A possible role of hormones which are often termed "hormones of youth"(growth hormone, melatonin, and
dehydroepiandrosterone) in the ageing process is discussed in the present article. Although some experimental and clinical data indicate that these hormones may play some role in the human ageing process, it appears from presented data that we are still far away from conclusion that, indeed, one (or more) of the discussed hormones could be considered as "hormone
of youth", which may slow down ageing process. However, some symptoms of the quality of life improvement following administration of dehydroepiandrosterone, melatonin, and growth hormone may suggest that they may promote so called "successful aging".
Abstract
Ageing is doubtless complicated, lifelong process regarding many body systems, including endocrine system. Human hormonal system changes with age. Although these changes concern secretion of many hormones, they are not unidirectional, there are hormones secretion of which is diminished, whereas secretion of the others is augmented or not changed with age. A possible role of hormones which are often termed "hormones of youth"(growth hormone, melatonin, and
dehydroepiandrosterone) in the ageing process is discussed in the present article. Although some experimental and clinical data indicate that these hormones may play some role in the human ageing process, it appears from presented data that we are still far away from conclusion that, indeed, one (or more) of the discussed hormones could be considered as "hormone
of youth", which may slow down ageing process. However, some symptoms of the quality of life improvement following administration of dehydroepiandrosterone, melatonin, and growth hormone may suggest that they may promote so called "successful aging".
Keywords
growth hormone; melatonin; DHEA; aging
Title
Hormones of youth?
Journal
Endokrynologia Polska
Issue
Vol 58, No 2 (2007)
Article type
Review paper
Pages
153-163
Published online
2007-03-13
Page views
585
Article views/downloads
9471
DOI
10.5603/ep.25646
Bibliographic record
Endokrynol Pol 2007;58(2):153-163.
Keywords
growth hormone
melatonin
DHEA
aging