open access

Vol 58, No 4 (2007)
Postgraduate education
Published online: 2007-05-17
Submitted: 2013-02-15
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The importance of presurgical somatostatin analogue therapy in acromegaly

Annamaria Colao
Endokrynologia Polska 2007;58(4):356-360.

open access

Vol 58, No 4 (2007)
Postgraduate education
Published online: 2007-05-17
Submitted: 2013-02-15

Abstract

Different types of treatment, including surgery, medical therapy and radiotherapy, are possible in achieving control of acromegaly. Of the medical therapies available, somatostatin analogues are effective in the majority of patients and can induce pituitary tumour shrinkage. The rationale and outcome of somatostatin analogue treatment before surgery in patients with acromegaly is briefly presented. In summary, the benefits of somatostatin analogues given preoperatively should be considered carefully as optimisation of cardiovascular, respiratory and metabolic functions is clinically relevant for perioperative morbidity. Somatostatin analogues also induce significant shrinkage of GH-secreting pituitary tumours, although this does not seem to be helpful in terms of improved surgical outcome. (Pol J Endocrinol 2007; 58 (4): 356-360)

Abstract

Different types of treatment, including surgery, medical therapy and radiotherapy, are possible in achieving control of acromegaly. Of the medical therapies available, somatostatin analogues are effective in the majority of patients and can induce pituitary tumour shrinkage. The rationale and outcome of somatostatin analogue treatment before surgery in patients with acromegaly is briefly presented. In summary, the benefits of somatostatin analogues given preoperatively should be considered carefully as optimisation of cardiovascular, respiratory and metabolic functions is clinically relevant for perioperative morbidity. Somatostatin analogues also induce significant shrinkage of GH-secreting pituitary tumours, although this does not seem to be helpful in terms of improved surgical outcome. (Pol J Endocrinol 2007; 58 (4): 356-360)
Get Citation

Keywords

acromegaly; somatostatin analogues; tumour shrinkage; pituitary tumour surgery

About this article
Title

The importance of presurgical somatostatin analogue therapy in acromegaly

Journal

Endokrynologia Polska

Issue

Vol 58, No 4 (2007)

Pages

356-360

Published online

2007-05-17

Bibliographic record

Endokrynologia Polska 2007;58(4):356-360.

Keywords

acromegaly
somatostatin analogues
tumour shrinkage
pituitary tumour surgery

Authors

Annamaria Colao

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