Vol 58, No 6 (2007)
Review paper
Published online: 2007-11-21
Subclinical hyperthyroidism
Endokrynol Pol 2007;58(6):536-542.
Abstract
Subclinical hyperthyroidism is a term used to define a clinical condition in which a reduced serum thyroid stimulating
hormone (TSH) level is accompanied by thyroxine and tri-iodothyronine levels within the reference ranges. It is a common
condition with the prevalence in the general population estimated on 0.6-16%. Subclinical hypethyroidism may progress
to overt hyperthyroidism and is associated with the risk of the development of cardiovascular complications (especially
atrial fibrillation), osteoporosis and dementia. Indications for the management of subclinical hyperthyroidism still remain
controversial. The aim of this paper is to familiarise the reader with the present state of knowledge on the prevalence,
etiopathogenesis, clinical manifestation, diagnosis, potential complications, prognosis and treatment of subclinical hyperthyroidism.
Keywords: subclinical hyperthyroidismetiopathogenesissymptomscomplicationsdiagnosistreatment
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