Vol 59, No 3 (2008)
Review paper
Published online: 2008-05-08
Obesity and bone metabolism
Endokrynol Pol 2008;59(3):218-223.
Abstract
Both bone and adipose tissue change their size, shape and distribution during the whole human being’s life. Many factors, including
genetic factors, hormones and activity of nervous system are responsible for these changes. It is generally accepted that obesity has
a protective effect on bone tissue. On the other hand some authors present an opposite results - the lack of beneficial effect of obesity on
development of osteoporosis fractures. The aim of this article was to present and discuss the relations between adipose tissue and bone
metabolism.
Keywords: obesityfracture riskPTHvitamin Dosteoprotegerinadipocytokines