open access

Vol 59, No 3 (2008)
Case report
Published online: 2008-05-08
Submitted: 2013-02-15
Get Citation

131I-MIBG therapy in the treatment of pheochromocytoma in children - own experiences

Kornelia Hasse-Lazar, Jolanta Krajewska, Ewa Paliczka-Cieślik, Beata Jurecka-Lubieniecka, Barbara Michalik, Daria Handkiewicz-Junak, Józef Roskosz, Barbara Jarząb
Endokrynologia Polska 2008;59(3):235-240.

open access

Vol 59, No 3 (2008)
Case report
Published online: 2008-05-08
Submitted: 2013-02-15

Abstract

Three cases of pheochromocytoma in children/adolescents or young adults treated by 131I-MIBG are presented in this study. In one patient 131I-MIBG was administrated after ineffective surgical treatment and chemotherapy of a benign retroperitoneal tumor, whereas in two other patients 131I-MIBG therapy was carried out because of malignant pheochromocytoma dissemination. In a child with retroperitoneal paraganglioma decrease of tumor size and its fibrosis after 131I-MIBG therapy allowed radical surgery and complete recovery. In two other cases partial remission was achieved. All patients showed a good subjective response with improvement of the general condition and better blood pressure control. In two children adverse reactions such as leucopenia, hypothyroidism or hypogonadism were observed. The presented data confirm effectiveness and acceptable tolerance of 131I-MIBG treatment in pheochromocytoma, what is very important in pediatric patients.

Abstract

Three cases of pheochromocytoma in children/adolescents or young adults treated by 131I-MIBG are presented in this study. In one patient 131I-MIBG was administrated after ineffective surgical treatment and chemotherapy of a benign retroperitoneal tumor, whereas in two other patients 131I-MIBG therapy was carried out because of malignant pheochromocytoma dissemination. In a child with retroperitoneal paraganglioma decrease of tumor size and its fibrosis after 131I-MIBG therapy allowed radical surgery and complete recovery. In two other cases partial remission was achieved. All patients showed a good subjective response with improvement of the general condition and better blood pressure control. In two children adverse reactions such as leucopenia, hypothyroidism or hypogonadism were observed. The presented data confirm effectiveness and acceptable tolerance of 131I-MIBG treatment in pheochromocytoma, what is very important in pediatric patients.
Get Citation

Keywords

Pheochromocytoma; 131I-MIBG therapy; children

About this article
Title

131I-MIBG therapy in the treatment of pheochromocytoma in children - own experiences

Journal

Endokrynologia Polska

Issue

Vol 59, No 3 (2008)

Pages

235-240

Published online

2008-05-08

Bibliographic record

Endokrynologia Polska 2008;59(3):235-240.

Keywords

Pheochromocytoma
131I-MIBG therapy
children

Authors

Kornelia Hasse-Lazar
Jolanta Krajewska
Ewa Paliczka-Cieślik
Beata Jurecka-Lubieniecka
Barbara Michalik
Daria Handkiewicz-Junak
Józef Roskosz
Barbara Jarząb

Important: This website uses cookies.tanya dokter More >>

The cookies allow us to identify your computer and find out details about your last visit. They remembering whether you've visited the site before, so that you remain logged in - or to help us work out how many new website visitors we get each month. Most internet browsers accept cookies automatically, but you can change the settings of your browser to erase cookies or prevent automatic acceptance if you prefer.

Via MedicaWydawcą serwisu jest  "Via Medica sp. z o.o." sp.k., ul. Świętokrzyska 73, 80–180 Gdańsk

tel.:+48 58 320 94 94, faks:+48 58 320 94 60, e-mail:  viamedica@viamedica.pl