open access

Vol 59, No 4 (2008)
Original paper
Submitted: 2013-02-15
Published online: 2008-07-09
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Thyroid incidentaloma in Isfahan, Iran - a population-based study

Fatemeh Jafary, Ashraf Aminorroaya, Massoud Amini, Atoosa Adibi, Mehri Sirous, Ehsan Roohi, Mohsen Mostafavi
Endokrynol Pol 2008;59(4):316-320.

open access

Vol 59, No 4 (2008)
Original Paper
Submitted: 2013-02-15
Published online: 2008-07-09

Abstract


Introduction: Thyroid nodules not detected in palpation but diagnosed following a radiological procedure or during surgery are called thyroid incidentalomas. We designed this study to investigate the prevalence of sonographic thyroid incidentaloma in Isfahan, Iran, for the first time.
Material and methods: By a multistage cluster sampling method, 2523 adults were selected randomly. From this group, 2045 had normal thyroid examination. 234 out of the 2045 were selected randomly for thyroid sonography. Thyroid stimulating hormone (TSH), urinary iodine concentrations (UIC) and antithyroid antibodies were measured.
Results: The prevalence of thyroid incidentaloma was 13.2% [Confidence interval (CI) 95% = 8–18]. The average age of subjects with and without incidentaloma was 46.1 (12.4) and 38.4 (12.1), respectively (P = 0.002). It was more prevalent in females than in males (19% vs. 10%) [Odds ratio (OR) = 2.59, CI 95% = 1.17–5.76, P value (P) = 0.01]. Median UIC in the incidentaloma group (14 μg/dl) was significantly lower than in the group of subjects without nodules (20 μg/dl) (OR = 0.9, CI 95% = 0.91–0.99, P = 0.02). There was no difference in the levels of TSH and antithyroid antibodies between the two groups (P > 0.05). Mean diameter of nodules was 8.14 (3.43) mm.
Conclusions: The prevalence of thyroid incidentaloma was 13.2% in Isfahan. It was higher in females than males and increased with age.

Abstract


Introduction: Thyroid nodules not detected in palpation but diagnosed following a radiological procedure or during surgery are called thyroid incidentalomas. We designed this study to investigate the prevalence of sonographic thyroid incidentaloma in Isfahan, Iran, for the first time.
Material and methods: By a multistage cluster sampling method, 2523 adults were selected randomly. From this group, 2045 had normal thyroid examination. 234 out of the 2045 were selected randomly for thyroid sonography. Thyroid stimulating hormone (TSH), urinary iodine concentrations (UIC) and antithyroid antibodies were measured.
Results: The prevalence of thyroid incidentaloma was 13.2% [Confidence interval (CI) 95% = 8–18]. The average age of subjects with and without incidentaloma was 46.1 (12.4) and 38.4 (12.1), respectively (P = 0.002). It was more prevalent in females than in males (19% vs. 10%) [Odds ratio (OR) = 2.59, CI 95% = 1.17–5.76, P value (P) = 0.01]. Median UIC in the incidentaloma group (14 μg/dl) was significantly lower than in the group of subjects without nodules (20 μg/dl) (OR = 0.9, CI 95% = 0.91–0.99, P = 0.02). There was no difference in the levels of TSH and antithyroid antibodies between the two groups (P > 0.05). Mean diameter of nodules was 8.14 (3.43) mm.
Conclusions: The prevalence of thyroid incidentaloma was 13.2% in Isfahan. It was higher in females than males and increased with age.
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Keywords

thyroid nodule; ultrasonography; Iran; adult

About this article
Title

Thyroid incidentaloma in Isfahan, Iran - a population-based study

Journal

Endokrynologia Polska

Issue

Vol 59, No 4 (2008)

Article type

Original paper

Pages

316-320

Published online

2008-07-09

Page views

589

Article views/downloads

1341

Bibliographic record

Endokrynol Pol 2008;59(4):316-320.

Keywords

thyroid nodule
ultrasonography
Iran
adult

Authors

Fatemeh Jafary
Ashraf Aminorroaya
Massoud Amini
Atoosa Adibi
Mehri Sirous
Ehsan Roohi
Mohsen Mostafavi

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