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Vol 60, No 3 (2009)
Review paper
Submitted: 2013-02-15
Published online: 2009-04-27
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The role of estrogens in angiogenesis in the female reproductive system

Bożena Dobrzycka, Maciej Kinalski, Dorota Piechocka, Sławomir J. Terlikowski
Endokrynol Pol 2009;60(3):210-214.

open access

Vol 60, No 3 (2009)
Review Article
Submitted: 2013-02-15
Published online: 2009-04-27

Abstract

Under physiological conditions, angiogenesis is routinely observed in the uterus. Multiple lines of evidence suggest that estrogen directly modulates angiogenesis via effects on endothelial cells. A clear association between estrogen, estrogen receptor expression by endothelial cells and angiogenic activity has been confirmed. This minireview will discuss the recent progress in research into the role of estrogens in angiogenesis.

Abstract

Under physiological conditions, angiogenesis is routinely observed in the uterus. Multiple lines of evidence suggest that estrogen directly modulates angiogenesis via effects on endothelial cells. A clear association between estrogen, estrogen receptor expression by endothelial cells and angiogenic activity has been confirmed. This minireview will discuss the recent progress in research into the role of estrogens in angiogenesis.

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Keywords

angiogenesis; estradiol (E2); estrogen (E); endothelial progenitor cell (EPCs); endothelial cells (EC); estrogen receptor (ER)

About this article
Title

The role of estrogens in angiogenesis in the female reproductive system

Journal

Endokrynologia Polska

Issue

Vol 60, No 3 (2009)

Article type

Review paper

Pages

210-214

Published online

2009-04-27

Page views

724

Article views/downloads

2790

Bibliographic record

Endokrynol Pol 2009;60(3):210-214.

Keywords

angiogenesis
estradiol (E2)
estrogen (E)
endothelial progenitor cell (EPCs)
endothelial cells (EC)
estrogen receptor (ER)

Authors

Bożena Dobrzycka
Maciej Kinalski
Dorota Piechocka
Sławomir J. Terlikowski

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