Vol 60, No 3 (2009)
Review paper
Published online: 2009-04-27
The role of estrogens in angiogenesis in the female reproductive system
Endokrynol Pol 2009;60(3):210-214.
Abstract
Under physiological conditions, angiogenesis is routinely observed in the uterus. Multiple lines of evidence suggest that estrogen directly
modulates angiogenesis via effects on endothelial cells. A clear association between estrogen, estrogen receptor expression by endothelial
cells and angiogenic activity has been confirmed. This minireview will discuss the recent progress in research into the role of estrogens in
angiogenesis.
Keywords: angiogenesisestradiol (E2)estrogen (E)endothelial progenitor cell (EPCs)endothelial cells (EC)estrogen receptor (ER)
