open access

Vol 60, No 4 (2009)
Postgraduate education
Published online: 2009-06-26
Submitted: 2013-02-15
Get Citation

Adrenal disorders in pregnancy

Bogdan Marek, Robert Krysiak, Bogusław Okopień
Endokrynologia Polska 2009;60(4):331-342.

open access

Vol 60, No 4 (2009)
Postgraduate education
Published online: 2009-06-26
Submitted: 2013-02-15

Abstract

Pregnancy dramatically affects the function of the adrenal glands and is associated with altered levels of adrenal hormones. Endocrine adaptation to pregnancy involves changes in the activities of the hypothalamic-pituitary-adrenal and renin-angiotensin-aldosterone axes. As a result, pregnancy may influence the course of pre-existing adrenal diseases or lead to their unmasking. Although disorders of the adrenal glands are rare during pregnancy, they may pose a serious health problem. The fact that some symptoms of adrenal disorders may be erroneously interpreted as symptoms of normal pregnancy together with overlapping their biochemical features make diagnosis of adrenal disorders in pregnancy difficult. Antenatal diagnosis and correct treatment of these disorders is necessary to prevent maternal and fetal morbidity and mortality. The aim of this paper is provide a scientific understanding of the normal function of adrenal glands in pregnancy and to discuss the pathophysiology, clinical manifestation, diagnosis and management of various adrenal disorders during pregnancy. We provide the reader with some practical recommendations concerning the approach to pregnant women with adrenal disturbances.

Abstract

Pregnancy dramatically affects the function of the adrenal glands and is associated with altered levels of adrenal hormones. Endocrine adaptation to pregnancy involves changes in the activities of the hypothalamic-pituitary-adrenal and renin-angiotensin-aldosterone axes. As a result, pregnancy may influence the course of pre-existing adrenal diseases or lead to their unmasking. Although disorders of the adrenal glands are rare during pregnancy, they may pose a serious health problem. The fact that some symptoms of adrenal disorders may be erroneously interpreted as symptoms of normal pregnancy together with overlapping their biochemical features make diagnosis of adrenal disorders in pregnancy difficult. Antenatal diagnosis and correct treatment of these disorders is necessary to prevent maternal and fetal morbidity and mortality. The aim of this paper is provide a scientific understanding of the normal function of adrenal glands in pregnancy and to discuss the pathophysiology, clinical manifestation, diagnosis and management of various adrenal disorders during pregnancy. We provide the reader with some practical recommendations concerning the approach to pregnant women with adrenal disturbances.
Get Citation

Keywords

pregnancy; adrenal function; adrenal disease; diagnosis; treatment

About this article
Title

Adrenal disorders in pregnancy

Journal

Endokrynologia Polska

Issue

Vol 60, No 4 (2009)

Pages

331-342

Published online

2009-06-26

Bibliographic record

Endokrynologia Polska 2009;60(4):331-342.

Keywords

pregnancy
adrenal function
adrenal disease
diagnosis
treatment

Authors

Bogdan Marek
Robert Krysiak
Bogusław Okopień

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